Sep 3, 2026; Columbia, Missouri, USA;  Missouri Tigers quarterback Austin Simmons (13) throws a pass against the Arkansas-Pine Bluff Golden Lions during the first half at Faurot Field at Memorial Stadium.  Mandatory Credit: Denny Medley-Imagn Images
IMAGN IMAGES via Reuters Connect

Missouri vs Kansas Prediction 9/11/2026 Today’s College Football Picks

Pick details

MATCHUP Missouri Tigers Kansas Jayhawks
Team Records 1-0 1-0
Spread -5.5 -108 +5.5 -112
Moneyline -205 +170
Total Over 50.5 (-115) Under 50.5 (-105)
Where David Booth Kansas Memorial Stadium, Lawrence, KS
When Friday, September 11, 2026
Time 08:00 PM EDT
TV FOX

The Missouri Tigers and the Kansas Jayhawks meet in week 2 college football action from David Booth Memorial Stadium on Friday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Missouri Tigers vs. Kansas Jayhawks Prediction.

Missouri Tigers Recap

The Missouri Tigers come into this game looking to add on to their 54-14 win over Arkansas Pine Bluff last time out to start the year at 1-0. After this game, Missouri will head home for a game against Troy.

Tigers Looking For Big Road Rivalry Win

Austin Simmons threw for 252 yards and 4 TDs on 17 of 19 passing while Matt Zollers added 87 yards on 8 of 12 passing and rushed for 26 yards and a score. Jamal Roberts rushed for 47 yards and a TD on 13 carries while Xai’Shaun Edwards added 45 rushing yards and Preston Hatfield chipped in 34 yards and a touchdown. Donovan Olugbode had a team-high 107 receiving yards and 2 TDs on 7 catches while Cayden Lee added 5 catches for 89 yards and a touchdown. Shaun Terry II added 55 receiving yards and a TD while Naeshaun Montgomery chipped in 3 catches for 47 yards. On defense, Jeremiah Beasley had a team-high 7 total tackles to lead Missouri’s defense, while Jason Dowell recorded 2 total tackles, a tackle for loss, and the team’s only sack.

Kansas Jayhawks Recap

The Kansas Jayhawks come into this game looking to add on to their 51-6 win over LIU last time out to start the year at 1-0. After this game, Kansas will take on Arizona state in a matchup at home.

Jayhawks Hoping To Emerge Victorious As Home Dog

Isaiah Marshall threw for 246 yards and 2 TDs on 14 of 19 passing while also rushing for 49 yards, and Cole Ballard added 90 yards on 4 of 6 passing. Yasin Willis led the ground game with 72 rushing yards and 2 TDs on 11 carries while Micah Johnson added 52 yards and a TD on 11 carries and Jalen Dupree chipped in 35 yards and a score. Nik McMillan had a team-high 130 receiving yards and a TD on 6 catches while Bryson Hayes added 2 catches for 56 yards and Tate Nagy chipped in 3 catches for 40 yards and a touchdown. On defense, Quincy Davis had a team-high 5 total tackles to lead Kansas’ defense, while Leroy Harris III logged 4 total tackles and a team-high 4 tackles for loss.

Missouri Tigers @ Kansas Jayhawks Betting Trends: Week 2


Why the Kansas Jayhawks will win

  • Kansas has won each of its last eight games against non-conference opponents at David Booth Kansas Memorial Stadium.
  • Missouri has lost four of its last five games as an AP-ranked team.
  • The team ranked 23rd in the AP Poll has failed to cover the spread in eight of its last nine games.
  • Kansas has covered the spread in five of its last six games as a home underdog.
  • Kansas has won the first quarter in each of its last six home games against non-conference opponents.
  • Kansas has won the first half in each of its last 10 home games against non-conference opponents.

Why the Missouri Tigers will win

  • Missouri has won each of its last 25 games against non-AP-ranked teams.
  • Kansas has lost eight of its last nine September games as a home underdog.
  • Missouri has covered the spread in each of its last eight road games against non-AP-ranked teams.
  • Kansas has failed to cover the spread in each of its last four games against teams from Missouri.
  • The team ranked 23rd in the AP Poll has won the first quarter in each of its last four games.
  • Kansas has lost the first half in eight of its last nine September games as a home underdog.

Total Points Facts

  • Each of Kansas’ last seven September games as a home underdog have gone OVER the total points line.
  • Each of Missouri’s last four road games have gone UNDER the total points line.

Kansas Jayhawks Player Prop Facts

  • Nik McMillan has recorded 100+ receiving yards in seven consecutive games – longest streak in the FBS, heading into Week 2.

Missouri Tigers Player Prop Facts

  • Heading into Week 2, Brett Norfleet ranks T1st amongst qualified players for catch rate (100.0%) this season.

Matchup/League Facts

  • Kansas ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
  • Kansas ranks T1st among FBS teams for Q2 opponent points per game this season (0.0).
  • Missouri ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
  • Missouri ranks T1st among FBS teams for Q2 opponent points per game this season (0.0).

Missouri Tigers vs. Kansas Jayhawks Prediction

I’m on Kansas and the points. This is a rivalry game plain and simple and getting Kansas as a home dog I think is where it’s at. The Jayhawks have their issues, and it’s hard to really get a read on either team after blowing out inferior competition in week 1, but in this spot, I want the points with KU.

Chris Ruffolo's Pick: Kansas +5.5

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