Sep 13, 2025; Lincoln, Nebraska, USA; Nebraska Cornhuskers running back Emmett Johnson (21) walks off after scoring against the Houston Christian Huskies during the second quarter at Memorial Stadium. Mandatory Credit: Dylan Widger-Imagn Images

Michigan vs Nebraska Prediction 9/20/2025 Today’s College Football Picks

Pick details

Michigan (2-1) vs Nebraska (3-0)

September 20, 2025 at 03:30 PM EDT

The Line: Betting Odds: Nebraska +2.5 — Over/Under: +45.5

(Get latest betting odds)

The Michigan Wolverines and Nebraska Cornhuskers meet Saturday in college football action at Memorial Stadium. Here’s a Michigan vs Nebraska Prediction. This article will include a Michigan vs Nebraska Pick.

Michigan Wolverines Betting Preview


The Michigan Wolverines beat Central Michigan, lost to Oklahoma, and they play Wisconsin next. Michigan has won 5 of its last 6 games. Bryce Underwood is completing 57.5 percent of his passes for 628 yards, 2 touchdowns, and 1 interception. Donaven McCulley and Semaj Morgan have combined for 279 receiving yards and 1 touchdown, while Channing Goodwin has 6 receptions.

The Michigan Wolverines ground game is averaging 242.7 yards per contest, and Justice Haynes leads the way with 388 yards and 5 touchdowns. Defensively, Michigan is allowing 14.7 points and 271.3 yards per game. Ernest Hausmann leads the Michigan Wolverines with 20 tackles, Jaishawn Barham has 2 sacks and Ty Guy has 1 interception.

Nebraska Cornhuskers Betting Preview


The Nebraska Cornhuskers beat Houston Christian and Akron, and they play Michigan State next. Nebraska has won 4 straight games. Dylan Raiola is completing 76.6 percent of his passes for 829 yards, 8 touchdowns, and 0 interceptions. Dane Key and Jacory Barney Jr. have combined for 371 receiving yards and 4 touchdowns, while Nyziah Hunter has 11 receptions.

The Nebraska Cornhuskers ground game is averaging 178.7 yards per contest, and Emmett Johnson leads the way with 326 yards and 4 touchdowns. Defensively, Nebraska is allowing 8 points and 202 yards per game. Rex Guthrie leads the Nebraska Cornhuskers with 12 tackles, Ashton Murphy has 1 sack and Malcolm Hartzog Jr. has 1 interception.

Michigan Wolverines @ Nebraska Cornhuskers Betting Trends: Week 4


Why the Nebraska Cornhuskers will win

  • Nebraska has won five of its last six games.
  • Michigan has lost three of its last four road games against conference opponents.
  • Nebraska has covered the spread in four of its last five home games in September.
  • Michigan has failed to cover the spread in seven of its last nine September games as a favorite.

Why the Michigan Wolverines will win

  • Nebraska has lost each of its last 13 home games against AP-ranked teams.
  • Michigan has won 37 of its last 38 games against non-AP-ranked teams.
  • Nebraska has failed to cover the spread in each of its last six games against AP-ranked teams at Memorial Stadium (Lincoln).
  • The team ranked 21st in the AP Poll has covered the spread in seven of its last eight games.

Total Points Facts


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  • Each of Michigan’s last six road games against non-AP-ranked teams have gone OVER the total points line.
  • Five of Nebraska’s last six games at Memorial Stadium (Lincoln) have gone OVER the total points line.

Nebraska Cornhuskers Player Prop Facts

  • Heading into Week 4, Emmett Johnson ranks 7th amongst FBS players for rushing yards (326) this season.

Michigan Wolverines Player Prop Facts

  • Heading into Week 4, Justice Haynes is one of only three players in the FBS to record 100+ rushing yards in three or more consecutive games this season.

Matchup/League Facts

  • Nebraska is one of only three FBS teams to ranks top 10 in points per game and points allowed per game this season.
  • Nebraska ranks 3rd among FBS teams for average point differential in second quarters this season (+19.3).
  • Michigan ranks T124th among FBS teams for 4th down conversion percentage this season (25.0).
  • Michigan ranks 15th among FBS teams for rushing yards per game this season (242.7).

Michigan vs Nebraska Prediction


Michigan is the better, more talented team, but it also struggled in its only road game this season and is still breaking in a young quarterback. Michigan has had a limited passing attack up to this point, and that doesn’t help against good teams. Nebraska has been explosive offensively and has one of the better defenses in the country, ranked sixth in total defense and seventh in scoring defense.

The Memorial Stadium will be rocking, and it’s fair to say there’s more confidence in Nebraska’s quarterback situation. Sometimes that’s the difference in the game. I’ll take the points in a game the Huskers could win outright.

Randy Chambers's Pick: Nebraska +2.5

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