Buffalo Bills vs New England Patriots Prediction 12/14/2025 Today’s NFL Picks

The Buffalo Bills and New England Patriots meet Sunday in NFL action at Gillette Stadium. Here’s a Buffalo Bills vs New England Patriots Prediction. This article will include a Buffalo Bills vs New England Patriots Pick.

Buffalo Bills Betting Preview

The Buffalo Bills beat the Steelers and Bengals, and they play the Browns next. The Bills have won 5 of their last 7 games. Josh Allen is completing 70.1 percent of his passes for 3,083 yards, 22 touchdowns, and 10 interceptions. Khalil Shakir and Dalton Kincaid have combined for 1,074 receiving yards and 9 touchdowns, while Keon Coleman has 36 receptions.

The Buffalo Bills ground game is averaging 157.8 yards per contest, and James Cook leads the way with 1,308 yards and 8 touchdowns. Defensively, Buffalo is allowing 22.5 points and 307.1 yards per game. Cole Bishop leads the Buffalo Bills with 71 tackles, Joey Bosa has 5 sacks and Maxwell Hairston has 2 interceptions.

New England Patriots Betting Preview

The New England Patriots beat the Bengals and Giants, and play the Ravens next. The New England Patriots have won 10 straight games. Drake Maye is completing 71.5 percent of his passes for 3,412 yards, 23 touchdowns, and 6 interceptions. Stefon Diggs and Hunter Henry have combined for 1,315 receiving yards and 8 touchdowns, while Kayshon Boutte has 29 receptions.

The New England Patriots ground game is averaging 112.9 yards per contest, and TreVeyon Henderson leads the way with 625 yards and 5 touchdowns. Defensively, New England is allowing 18.5 points and 296.4 yards per game. Robert Spillane leads the New England Patriots with 97 tackles, Harold Landry III has 7.5 sacks and Marcus Jones has 3 interceptions.

Why the New England Patriots will win

• The Patriots have won each of their last nine games following a win.
• The Bills have lost four of their last five games as road favorites following a win.
• The Bills have failed to cover the spread in each of their last six games as favorites following a win.
• The Patriots have covered the spread in each of their last five games against the Bills.
• The Bills have lost the first quarter in three of their last four games as favorites following a win.
• The Bills have lost the first half in each of their last four games against AFC opponents.

Why the Buffalo Bills will win

• The Bills have won each of their last nine Week 15 games.
• The Patriots have lost 10 of their last 11 December home games against AFC opponents.
• The Bills have covered the spread in nine of their last 10 Sunday games against teams that held a winning record.
• The Patriots have failed to cover the spread in each of their last five December home games against AFC East opponents.
• The Patriots have lost the first quarter in each of their last four Week 15 games.
• The Patriots have lost the first half in each of their last five games as home underdogs following a win.

Total Points Facts

• Eight of the Patriots’ last nine games in December have gone OVER the total points line.
• Five of the Bills’ last six road games have gone UNDER the total points line.
• Eight of the last 10 Sunday games at Gillette Stadium have gone OVER the total points line.

New England Patriots Player Prop Facts

• Drake Maye has recorded 259+ passing yards in each of the Patriots’ last six games following a win.
• TreVeyon Henderson has recorded 55+ rushing yards in each of the Patriots’ last six games following a win.
• TreVeyon Henderson has recorded 75+ rushing and receiving yards in each of the Patriots’ last six games.
• Drake Maye has recorded 22+ completions in four of the Patriots’ last five games as underdogs following a win.
• Joshua Dobbs has scored a touchdown in each of his last four appearances with his team as an underdog against teams that held a winning record.
• Austin Hooper has recorded 16+ receiving yardsin each of his last 13 appearances with his team as an underdog in games with a total points line of at least 50.0.
• Heading into Week 15, Drake Maye has the most games with a 100+ passer rating this season (10).

Buffalo Bills Player Prop Facts

• Josh Allen has scored two touchdowns in four of the Bills’ last five games against teams on a winning streak.
• Josh Allen has recorded 21+ completions in each of the Bills’ last six games as favorites with a total points line of at least 50.0.
• Josh Allen has scored at least one touchdown in 15 of the Bills’ last 16 games against teams on a winning streak.
• Keon Coleman has recorded 20+ receiving yards in each of the Bills’ last six games against AFC East opponents.
• Josh Allen has recorded 253+ passing yards in each of the Bills’ last six road games with a total points line of at least 50.0.
• James Cook has recorded 111+ rushing and receiving yards in each of the Bills’ last four games as favorites.
• James Cook has recorded 87+ rushing yards in five of the Bills’ last six games as road favorites.
• Heading into Week 15, James Cook has recorded the equal-most rushing attempts in a single game this season (32 vs Steelers, Week 13).

Matchup/League Facts

• Patriots – six different players have recorded 80+ receiving yards in a game this season – most in the NFL, heading into Week 15.
• Patriots – five different players have recorded 90+ receiving yards in a game this season – equal-most in the NFL, heading into Week 15.
• Heading into Week 15, the Bills rank 1st in the NFL in rushing yards per game (157.8) this season.
• Heading into Week 15, the Bills rank 32nd in the NFL in average punt return (5.3 yards) this season.

Buffalo Bills vs New England Patriots Prediction

You can make a strong case for the Bills, as they’re in must-win territory and Josh Allen is one of those guys capable of putting the team on his back and just finding a way. However, the Patriots haven’t lost a game since week 3, and they’re at home with the rest advantage. i love my dogs that have had extra time to prepare. I understand the Pats have won 10 straight games, covered 7 of those games, and you’re just waiting for a slip-up. It can happen. I’m just not turning down free points with a team that keeps winning and has proven to be legit with a top-10 scoring offense and scoring defense. The underdog has covered 7 of the last 10 games between the Patriots and Bills. I’m going to take the points with the Patriots at home.

Randy Chambers's Pick: New England +1.5