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San Antonio Spurs vs Los Angeles Lakers Prediction 3/17/25 NBA Picks

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Los Angeles Lakers (41-25) vs San Antonio Spurs (28-38)

March 17, 2025 at 10:30 PM EDT

The Line: Betting Odds: Los Angeles Lakers -9 — Over/Under: 229

(Get latest betting odds)

The San Antonio Spurs and LA Lakers meet Monday in NBA action at the crypto.com Arena. Here’s a San Antonio Spurs vs LA Lakers Prediction. This article will include a San Antonio Spurs vs LA Lakers Pick.

San Antonio Spurs Betting Preview 

The San Antonio Spurs lost to the Hornets, beat the Pelicans, and then play the Knicks, 76ers, Raptors, and Pistons next. The Spurs have lost 10 of their last 15 games and are 3.5 games out of a play-in spot. 

The San Antonio Spurs are averaging 114.2 points on 46.6 percent shooting and allowing 116.6 points on 47.3 percent shooting. Devin Vassell is averaging 15.9 points and 3.8 rebounds, while Stephon Castle is averaging 13.4 points and 3.5 assists. Keldon Johnson is the third double-digit scorer and Harrison Barnes is dishing 1.7 assists. The San Antonio Spurs are shooting 35.2 percent from beyond the arc and 77.3 percent from the free-throw line. The San Antonio Spurs are allowing 36.3 percent shooting from deep and are grabbing 44 rebounds per game.

LA Lakers Betting Preview 

The LA Lakers lost to the Nuggets, beat the Suns, and they play the Nuggets, Bucks, and Bulls next. The Lakers have lost four of their last five games, but their last seven wins have come at home. 

The LA Lakers are averaging 113 points on 47.9 percent shooting and allowing 111.7 points on 46 percent shooting. LeBron James is averaging 25 points and 8.2 rebounds, while Luka Doncic is averaging 26.1 points and 8.6 rebounds. Austin Reaves is the third double-digit scorer and Rui Hachimura is grabbing 5.2 rebounds. The LA Lakers are shooting 35.7 percent from beyond the arc and 78.7 percent from the free-throw line. The LA Lakers are allowing 35 percent shooting from deep and are grabbing 42.8 rebounds per game.

Why the Los Angeles Lakers will win

  • The Lakers have won each of their last 12 home games following a win.
  • The Spurs have lost each of their last 11 games as underdogs after winning as underdogs.
  • The Lakers have covered the spread in each of their last eight games at Crypto.com Arena following a home win.
  • The Spurs have failed to cover the spread in nine of their last 10 games following a win.

Why the San Antonio Spurs will win

  • The Spurs have won 10 of their last 11 road games against the Lakers following a win.
  • The Lakers have lost four of their last five games.
  • The Lakers have failed to cover the spread in each of their last four night games against Spurs teams that held a losing record.
  • The Spurs have covered the spread in four of their last five road games against the Lakers following a win.

Matchup/League Facts

  • The Lakers rank 28th in the league for Q4 win percentage this season (39.4%).
  • The Lakers rank 4th in the league for opponent blocks per game this season (4.2).
  • The Spurs rank 2nd in the league for Q3 win percentage this season (62.1%).
  • The Spurs rank 28th in the league for opponent offensive rebounds per game this season (12.2).

San Antonio Spurs vs LA Lakers Injury Report 

The LA Lakers will be without Maxi Kleber, LeBron James, and Rui Hachimura. Trey Jemison III is questionable after not playing yesterday.

The San Antonio Spurs will be without Riley Minix, De’Aaron Fox, Victor Wembanyama, and Charles Bassey. Jordan McLaughlin is questionable with an Achilles injury. 

San Antonio Spurs vs LA Lakers Prediction

I’m not excited to lay a big number with a banged-up Lakers team that’s on the end of a back-to-back. However, the Lakers should still win this game comfortably when you factor in the Spurs’ form and injuries. The Spurs have been going nowhere fast over these last few weeks and there’s just not enough healthy talent to compete most nights, especially against above-average teams. The Lakers are fighting for home-court advantage in the first round of the playoffs and they can’t afford to blow games like this. I’ll lay the points with the Lakers, but it’s not my favorite game on the NBA card.

Randy Chambers's Pick: Lakers -9

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