San Francisco Giants vs Los Angeles Dodgers Prediction 9/19/2025 Today’s MLB Picks

The San Francisco Giants and Los Angeles Dodgers meet Friday in MLB action at Dodger Stadium. Here’s a San Francisco Giants vs Los Angeles Dodgers Prediction. This article will include a San Francisco Giants vs Los Angeles Dodgers Pick.

San Francisco Giants Betting Preview

The San Francisco Giants are 76-77 on the year and play the Cardinals and Rockies next. The San Francisco Giants are batting .235 on the season, have a .311 OBP, and a .385 slugging percentage. The San Francisco Giants pitching staff has a 3.83 ERA and a 1.30 WHIP. Heliot Ramos leads the San Francisco Giants with 149 hits and 61 RBI, while Jung Hoo Lee and Willy Adames have combined for 265 hits and 134 RBI.

Robbie Ray gets the ball for the San Francisco Giants, and he is 11-7 with a 3.50 ERA and 181 strikeouts this season. Ray is 9-7 with a 3.54 ERA and 184 strikeouts in his career against the Los Angeles Dodgers.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 86-67 on the year and play the Diamondbacks and Mariners next. The Los Angeles Dodgers are batting .254 on the season, have a .329 OBP, and a .439 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.03 ERA and a 1.27 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 164 hits and 95 RBI while Freddie Freeman and Andy Pages have combined for 307 hits and 165 RBI.

Clayton Kershaw gets the ball for the Los Angeles Dodgers, and he is 10-2 with a 3.53 ERA and 71 strikeouts this season. Kershaw is 27-16 with a 2.08 ERA and 415 strikeouts in his career against the San Francisco Giants.

San Francisco Giants @ Los Angeles Dodgers Betting Trends: September 19, 2025

• Probable Starting Pitcher: Clayton Kershaw      Record this season: 10-2      ERA: 3.53
• Home Record: 5-0
• Last 5 against Giants: 2-1

Why the Los Angeles Dodgers will win

• The Dodgers have won each of their last five home games against NL West opponents.
• The Giants have lost each of their last four night games against National League opponents.
• The Dodgers have covered the run line each of their last three home games against teams that held a losing record.

• Probable Starting Pitcher: Robbie Ray      Record this season: 11-7      ERA: 3.50
• Road Record: 6-3
• Last 5 against Dodgers: 2-2

Why the San Francisco Giants will win

• The Giants have won six of their last seven night games against the Dodgers following a loss.
• The Dodgers have lost four of their last five Friday games as favorites against NL West opponents.
• The Dodgers have failed to cover the run line in each of their last nine Friday night games as favorites against National League opponents.
• The Giants have covered the run line each of their last six road games against National League opponents that held a winning record.

Total Runs Facts

• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Dodgers’ last four home games against NL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Giants’ last six Friday night games.

Los Angeles Dodgers Player Prop Facts

• Clayton Kershaw has recorded a win in six of his last seven appearances with the Dodgers as favorites.
• Mookie Betts has hit a home run in three of the Dodgers’ last four games against NL opponents that held a losing record.
• Clayton Kershaw has recorded four or more strikeouts in each of his last 43 appearances at Dodger Stadium against NL West opponents that held a losing record.
• Mookie Betts has recorded at least one hit in 18 of his last 19 appearances against opponents that held a losing record.
• Shohei Ohtani ranks 2nd amongst qualified players for On Base Percentage (.395) this season.

San Francisco Giants Player Prop Facts

• Dominic Smith has recorded a Double in three of his last four appearances at Dodger Stadium.
• Dominic Smith has recorded at least one hit in 10 of his last 11 appearances in night games against teams that held a winning record.
• Wilmer Flores has hit a home run in three of his last seven appearances in night games.

Matchup/League Facts

• The Dodgers rank 2nd in the league for slugging percentage this season (.439).
• The Dodgers rank 2nd in the league for walks this season (557).
• The Giants rank 26th in the league for hits this season (1193).
• The Giants rank T26th in the league for doubles this season (225).

San Francisco Giants vs Los Angeles Dodgers Prediction

The Giants are worth a look with Ray on the mound, as he’s been a top-25 pitcher this season and has a 3.28 ERA and .203 allowed batting average on the road. However, the Giants have fallen off a cliff over the last two weeks and are on the outside looking in regarding the wild card race. Ray has also allowed 22 hits and 17 earned runs in his last 18 innings, which includes just getting tagged by these Dodgers. Kershaw is having a shaky September, but he’s been solid overall, and the Dodgers have won 7 of his last 8 starts. There should also be an electric atmosphere after Kershaw said he’s retiring after the season. Expect some extra juice. Give me the Dodgers.