San Diego Padres vs Seattle Mariners Prediction 8/27/2025 Today’s MLB Picks

In this article, we will formulate a Padres vs Mariners Prediction for this MLB game on Wednesday, August 27^th at the T-Mobile Park in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Preview

The Seattle Mariners have a 71-62 record this season and are sitting on the second place of the AL West. The Mariners have a 40-27 home record and are 72-55 in over/under. They are coming off a 6-7 home defeat by the Mariners, which ended their two-game winning streak. Over is 7-2 in their last 9 games and they are playing the Rays and the Guardians next.

The Mariners have a .242 batting average this season, .318 OBP and .411 Slugging percentage. Seattle’s pitching staff has a 3.98 ERA and 1.26 WHIP. Julio Rodriguez leads the Mariners in hits with 142, while JP Crawford is the team’s best hitter with a .264 batting average. Cal Raleigh leads the team both in RBI with 107, and in home runs with 50.

Bryan Woo (R) is the projected starting pitcher for the Mariners, and he has a 11-7 record, 2.97 ERA and 0.94 WHIP.

San Diego Padres Preview

The San Diego Padres have a 75-58 record this season and are sitting on the second place of the NL West. They have a 32-36 road record, and are 56-73 in over/under. The Padres are coming off a 7-6 road victory over the Mariners, which ended their two-game losing streak. Over is 3-0 in their last 3 games and are playing the Twins and the Orioles next. 

The Padres have a .252 batting average this season, .322 OBP and .386 Slugging percentage. San Diego’s pitching staff has a 3.59 ERA and 1.19 WHIP. Manny Machado leads the Padres with 149 hits and is the team’s best hitter with a .290 batting average. He also leads the team in RBI, with 78, and in home runs, with 21. 

Yu Darvish (R) is the projected starting pitcher for the Padres, and he has a 3-3 record, 5.36 ERA and 1.10 WHIP.

Why the Seattle Mariners will win

• The Mariners have won nine of their last 10 games at T-Mobile Park following a loss.
• The Padres have lost each of their last five games against the Mariners following a win.
• The Padres have failed to cover the run line in nine of their last 10 road games against American League opponents following a win.
• The Mariners have covered the run line in each of their last five games against the Padres following a loss.
• The Padres have lost the first inning in three of their last four games against AL West opponents.
• The Padres have trailed after 5 innings in each of their last five road games.
• The Mariners have led after 3 innings in each of their last four home day games.

Why the San Diego Padres will win

• The underdogs have won seven of the last eight games between the Padres and Mariners.
• The Mariners have lost four of their last five games as favorites against National League opponents.
• The Padres have covered the run line in 12 of their last 13 games as underdogs following a win.
• The Mariners have failed to cover the run line in eight of their last nine games as favorites against National League opponents.
• The Padres have led after 5 innings in seven of their last eight day games.
• The Mariners have trailed after 3 innings in each of their last seven games against National League opponents that held a winning record.

Total Runs Facts

• Each of the Padres’ last six day games against AL West opponents have gone UNDER the total runs line.
• Each of the Mariners’ last six games against National League opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Mariners’ last eight games as favorites against NL West opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Padres’ last eight day games against AL West opponents.

Matchup/League Facts

• The Mariners rank 29th in the league for doubles this season (181).
• The Mariners rank 29th in the league for triples this season (7).
• The Padres rank 1st in the league for opponent batting average this season (.223).
• The Padres rank 1st in the league for hits allowed this season (970).

Padres vs Mariners Prediction

The Mariners are 9-2 in their last 11 head-to-head meetings against the Padres, and are 4-2 their last 4 meetings in Seattle.

In this Padres vs Mariners Prediction, the Mariners are coming as -135 home favorites. The Mariners have the pitching advantage, as Woo takes the mound and he has been elite this season, and even stronger at home, with a 2.28 home ERA. He is back into form, with back-to-back quality starts, while on the other hand, Darvish has not been himself this season for the Padres, and he has been struggling on the road, with a 7.66 road ERA across five road starts. I like this bounce-back spot for the home team, so give me the Mariners on the moneyline at home in a decent price.