Arizona Diamondbacks vs New York Yankees Prediction 4/2/25 MLB Picks

The projected starting pitcher for the Diamondbacks is Zac Gallen, who had a 14-6 record in 28 starts last season with a 3.65 ERA and 1.26 WHIP over 148.0 innings of work. Gallen struggled in his previous start as he took a loss against the Cubs, posting a 9.00 ERA in 4.0 innings.

New York Yankees Betting Preview

The New York Yankees (3-1, 3-1 Home) dismantled the Milwaukee Brewers in the first series of the season. The Yanks won all three duels and scored 36 runs in the process! Still, the Yankees couldn't get the fourth consecutive victory as they fell to the Arizona Diamondbacks 7-5 in the opening game of this series. Will Warren was solid in his start as he allowed two runs on one hit with four strikeouts and four walks in 5.0 innings for a no-decision.

This year, the Yankees average 12.00 runs per game (1st in the MLB) on a .333/.427/.804 triple-slash. When it comes to pitching, the Yankees’ staff has a 3.33 ERA (10th) and 1.26 WHIP (13th). Aaron Judge leads the Yankees with a .400 batting average, four home runs, and 11 RBI this season.

Carlos Rodon will take the mound for the Yankees on Wednesday. The 32-year-old southpaw had a 16-9 record last season in 32 starts with a 3.96 ERA and 1.22 WHIP in 175.0 innings. This season, Rodon secured a win over the Brewers as he posted a 1.69 ERA over 5.1 innings of work.

Why the Diamondbacks will beat the Yankees

• The Diamondbacks have won each of their last 13 Wednesday games.
• The Yankees have lost each of their last six Wednesday night games as favorites against National League opponents.
• The Diamondbacks have covered the run line in each of their last nine Wednesday games.
• The Yankees have failed to cover the run line in each of their last seven Wednesday games as favorites.

Why the Yankees will beat the Diamondbacks

• The Yankees have won six of their last seven night games following a home loss.
• The Diamondbacks have lost four of their last five games following a win.
• The favorites have covered the run line in 13 of the Yankees' last 15 games.
• The Diamondbacks have failed to cover the run line in three of their last four games following a win.
• The Diamondbacks have trailed after 5 innings in four of their last five road games against American League opponents that held a winning record.

Total Runs Facts

• Eight of the Yankees' last nine home games after playing the previous day have gone OVER the total runs line.
• Seven of the Diamondbacks' last eight road games against American League opponents have gone OVER the total runs line.
• The 'Inning 1 OVER 0.5 runs' market has hit in each of the Yankees' last seven games as favorites against National League opponents.
• The 'Inning 1 UNDER 0.5 runs' market has hit in each of the Diamondbacks' last four road games against American League opponents.

Diamondbacks vs Yankees Prediction

These teams have traded victories in the past few years, as each recorded five in the previous ten H2H encounters. Gallen shut the Yanks out in his last start against them, while Rodon had a 3.38 ERA in his most recent showing against the D-backs. New York has a .260 BA against right-handers, while Arizona has a .219 against southpaws this year, which is not very promising if you want to back Over. Considering how these offenses opened this season, we should expect 10+ runs with ease, but this particular pitching matchup's got me thinking, so I am opting for Under instead.