Minnesota Twins vs St. Louis Cardinals Prediction 3/29/25 MLB Picks

-Recent Betting trends and streaks involving Minnesota

-Recent Betting trends and streaks involving St. Louis

-Recent betting trends in games played between Minnesota and St Louis

-A summary that ties it all together produces a favorable betting outcome for Today’s Game between the Twins and Cardinals.

Already Problems for the Twins? 

Last season, the biggest issue for the Twins was inconsistency with offense and injuries, and it appears that the team might have the same issues in one game into the season. The Twins scored their first two runs in the fifth inning, but they only added one more for the rest of the game, and they ended up losing 5-3. Pablo Lopez only gave up two runs, but he did give up eight hits in five innings, and he was playing with fire. Harrison Bader did find some success against his former team, hitting a home run and driving in two RBIs. 

Joe Ryan is going to get the start for the Twins, and he is considered by some the ace of the staff. Last season, Ryan finished with a 7-7 record and an ERA of 3.60. During spring training, Ryan had a 2-1 record but a high ERA of 5.54. After this series, the Twins will head to the South Side to take on the Chicago White Sox. 

Cardinals' Pitching Was Strong

The Cardinals' pitching was strong on Thursday, and it’s going to need to be the same here. Sonny Gray got the start, and he went five innings, giving up four hits and two runs. The Bullpen came in and was also strong, outside of Kyle Leahy, who gave up a run in 0.2 innings. Lars Nootbarr was the star of the show, and he finished the game with a run, two hits, two runs, and two RBIs. Nolan Arenado also finished with two hits and a home run. If the long ball is flying, this will be another strong game. 

Erick Fedde will start for the Cardinals. Last season, he split time between the Chicago White Sox and Cardinals. With the Cardinals, he went 2-5 and finished with an ERA of 3.72. After this series, the Cardinals will meet the Angels and Red Sox.

Why the Cardinals Will Beat the Twins

• The Twins have lost each of their last five games as favorites.
• The Cardinals have won five of their last six games as underdogs.
• The Twins have failed to cover the run line in eight of their last nine games.
• The Cardinals have covered the run line in eight of their last nine games as underdogs.
• The Cardinals have led after 5 innings in five of their last six games.
• The Cardinals have led after 3 innings in four of their last five games at Busch Stadium against American League opponents that held a losing record.

Minnesota Twins vs St. Louis Cardinals Prediction

Was Joe Ryan’s big weakness last season? Giving up the long ball. What did the Cardinals find success doing on Thursday? Hitting the long ball. This Twins offense has gotten out to slow starts the last couple of seasons, and it’s not going to be any different here. Their bats are going to be ice cold, and they are going to make Fedde like a Cy Young winner. Ryan might give up only a couple of runs, but those couple of runs are going to be the difference. Back the Cardinals on the money line.