Wyoming vs Grand Canyon Prediction 2/21/2026 Today’s College Basketball Picks

In this article, we will formulate a Wyoming vs Grand Canyon Prediction for this college basketball game on Saturday, February 21st. Let’s take a look at the prediction for this college basketball matchup.

Grand Canyon Lopes Preview

The Grand Canyon Lopes have a 17-9 overall record and a 10-5 record in the Mountain West. They are coming off a 73-63 road win against San Diego State and their previous three games were a 94-79 road win against San Jose State, a 70-64 home loss against New Mexico and an 80-78 road loss against UNLV.

Offensively, Grand Canyon averages 75.2 points per game, while allowing 68.5 points per game defensively. The Lopes shoot with 45% from the field and grab 36.4 rebounds per game, while dishing out 12.6 assists per game. They average 3.5 blocks per game and 6.9 steals per game defensively.

Jaden Henley leads Grand Canyon in scoring, with an average of 17.5 points per game, while shooting with 46% from the field and 77.9% from the free throw line, adding a team-high 2.8 assists. Nana Owusu-Anane is the team’s leading rebounder with 8.5 per game.

Wyoming Cowboys Preview

The Wyoming Cowboys have a 14-12 overall record and a 5-10 record in the Mountain West. They are coming off a 92-82 home win against Fresno State and their previous three games were a 79-68 road loss against Colorado State, an 85-83 home loss against Utah State and a 72-63 road loss against San Diego State.

Offensively, Wyoming averages 78 points per game, while allowing 73.5 points per game defensively. The Cowboys shoot with 45% from the field and grab 35.9 rebounds per game, while dishing out 14.2 assists per game. They average 2.5 blocks per game and 6.6 steals per game defensively.

Leland Walker leads Wyoming in scoring, with an average of 14.6 points per game, while shooting with 44.6% from the field and 82.6% from the free throw line, adding a team-high 3.6 assists. Khaden Bennett is the team’s leading rebounder with 5.1 per game.

Wyoming Cowboys @ Grand Canyon Antelopes Betting Trends: February 21, 2026

Why the Grand Canyon Antelopes will win

• Wyoming has lost each of its last seven road night games against Conference opponents.
• Grand Canyon has won 17 of its last 18 Saturday games at Global Credit Union Arena at GCU.
• Wyoming has lost the first half in five of its last six road night games against Conference opponents.

Why the Wyoming Cowboys will win

• The road team has won each of Grand Canyon’s last three games.
• Grand Canyon has lost the first half in three of its last four games.

Total Points Facts

• Five of Grand Canyon’s last six home games against non-AP-ranked opponents have produced a total of 139 or fewer points.
• Each of Wyoming’s last three games have produced a total of 147+ points.

Matchup/League Facts

• Grand Canyon ranks 34th among Division 1 teams for opponent field goals made per game this season (23.1).
• Grand Canyon ranks 45th among Division 1 teams for opponent assists per game this season (11.6).
• Wyoming ranks 14th among Division 1 teams for opponent field goal attempts per game this season (53.2).
• Wyoming ranks 23rd among Division 1 teams for opponent rebounds per game this season (30.9).

Wyoming vs Grand Canyon Prediction

In this Wyoming vs Grand Canyon Prediction, Grand Canyon is coming as -8 home favorites. Grand Canyon has been the better team this season and has been in very good form altely, with a 7-3 record in its last 10 games. On the flip side, Wyoming has been terrible on the road, with a 1-8 straight up record and 2-7 ATS record and are 3-7 in their last 10 games, so I like the value with the home team, which also boasts the 35th-best defense in the entire nation. Take Grand Canyon and lay the points at home.

Nikos Lagouretos's Pick: Grand Canyon -8