St. Mary’s vs Vanderbilt Prediction 11/28/2025 Today’s College Basketball Picks

The Vanderbilt Commodores and the Saint Mary’s Gaels meet Friday in college basketball action from the Imperial Arena at Atlantis Resort. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Vanderbilt Commodores vs. Saint Mary’s Gaels prediction.

Vanderbilt Commodores Recap

The Vanderbilt Commodores come into this game looking to add on to their 89-74 win over VCU last time out to sit at 7-0 on the year.

Commodores Looking To Stay Perfect

Duke Miles leads the Commodores in scoring with 17.5 PPG and 5.2 APG while Tyler Tanner has 15.2 PPG with 4.2 APG and 2.5 SPG. Tyler Harris has 12 PPG with 4.3 RPG and Tyler Nickel has 13.5 PPG with 4 RPG and AK Okereke has 10.2 PPG with 3.7 RPG. Devin McGlockton has 12.3 PPG with 6.7 RPG to lead Vanderbilt in rebounding to cap off the group of double-digit scorers for Vanderbilt so far this season. Frankie Collins also has 9.3 PPG with 4.8 RPG and a team-high 6.2 APG along with 3.7 SPG to lead Vanderbilt in assists and steals so far this season. As a team, Vanderbilt is averaging 99.7 PPG on 52% shooting from the field, 38.9% from three and 73.9% from the foul line this season.

Saint Mary’s Gaels Recap

The Saint Mary’s Gaels come into this game looking to build on a 77-66 win over Virginia Tech last time out to sit at 8-0 this season. 

Gaels Win 8 Straight To Start Year

Mikey Lewis leads the Gaels in scoring with 19 PPG along with 3.7 RPG and 4 APG while Paulius Murauskas has 18.6 PPG with 7.3 RPG. Joshua Dent has 11.4 PPG with a team-high 4.9 APG to lead the Gaels in assists and to round out the group of double-digit scorers for St. Mary’s up to this point in the year. Liam Campbell has 7.6 PPG and Andrew McKeever has 8.7 PPG with a team-high 11.1 RPG to lead the Gaels in rebounding up to this point in the year. As a team, St. Mary’s is averaging 84.6 PPG on 48.4% shooting from the field, 42.1% from three and 79.9% from the foul line this season. 

Vanderbilt Commodores @ Saint Mary’s Gaels Betting Trends: November 28, 2025

Why the Saint Mary’s Gaels will win

• Saint Mary’s has won each of its last eight games.
• Vanderbilt has lost each of its last three games against the West Coast Conference.
• Saint Mary’s has won the first half in each of its last eight games.

Why the Vanderbilt Commodores will win

• Vanderbilt has won each of its last seven games.
• Saint Mary’s has lost eight of its last 10 games against AP-ranked opponents at a neutral venue.
• Vanderbilt has won the first half in each of its last 14 games against non-Conference opponents.

Total Points Facts

• Each of Saint Mary’s’ last 43 games at a neutral venue have produced a total of 151 or fewer points.
• Each of Vanderbilt’s last 12 Friday games against non-Conference opponents have produced a total of 149 or fewer points.

Matchup/League Facts

• Saint Mary’s ranks 5th among Division 1 teams for opponent points per game this season (59.8).
• Saint Mary’s ranks 5th among Division 1 teams for opponent field goal percentage this season (35.6%).
• Vanderbilt ranks 2nd among Division 1 teams for points per game this season (98.1).
• Vanderbilt is one of two teams to ranks in the top-10 for both points and assists per game this season.

Vanderbilt Commodores vs. Saint Mary’s Gaels Prediction

I’m on Vanderbilt here. I just think the Commodores are no slouch and while the Gaels are a sharp team defensively, I just think Vandy has too much firepower. Mark Byington has done a heck of a job with Vanderbilt and ultimately I like them to win this game. Give me Vanderbilt in this one.

Chris Ruffolo's Pick: Vanderbilt -3.5