Dec 20, 2025; Detroit, Michigan, USA;  Detroit Pistons guard Jaden Ivey (23) reacts in the second half against the Charlotte Hornets at Little Caesars Arena. Mandatory Credit: Rick Osentoski-Imagn Images
Rick Osentoski-Imagn Images

Detroit Pistons vs Portland Trail Blazers Prediction 12/22/2025 Today’s NBA Picks

Pick details

MATCHUP Detroit Pistons Portland Trailblazers
Team Records 22-6 12-16
Spread -5.5 -115 +5.5 -105
Moneyline -238 +195
Total Over 234.5 (-115) Under 234.5 (-105)
Where Moda Center, Portland, OR
When Monday, December 22, 2025
Time 10:00 PM EST
TV KUNP 16

The Detroit Pistons and Portland Trail Blazers meet Monday in NBA action at the Moda Center. Here’s a Detroit Pistons vs Portland Trail Blazers Prediction. This article will include a Detroit Pistons vs Portland Trail Blazers Pick.

Detroit Pistons Betting Preview


The Detroit Pistons beat the Hornets, lost to the Mavs, and they play the Kings next. The Pistons have won 20 of their last 24 games.

The Detroit Pistons are averaging 119.4 points on 48.5 percent shooting and allowing 113 points on 44.7 percent shooting. Cade Cunningham is averaging 27.1 points and 6 rebounds, while Jalen Duren is averaging 18 points and 1.7 assists. Tobias Harris is the third double-digit scorer and Duncan Robinson is grabbing 3 rebounds. The Detroit Pistons are shooting 35.6 percent from beyond the arc and 74.8 percent from the free-throw line. The Detroit Pistons are allowing 35.7 percent shooting from deep and are grabbing 46.2 rebounds per game.

Portland Trail Blazers Betting Preview


The Portland Trail Blazers beat the Warriors and Kings, and they play the Magic next. The Trail Blazers have won 3 straight games.

The Portland Trail Blazers are averaging 118.2 points on 44.4 percent shooting and allowing 121.9 points on 48.2 percent shooting. Deni Avdija is averaging 25.5 points and 7.2 rebounds, while Shaedon Sharpe is averaging 21.7 points and 4.6 rebounds. Jerami Grant is the third double-digit scorer and Jrue Holiday is grabbing 5.3 rebounds. The Portland Trail Blazers are shooting 33.5 percent from beyond the arc and 80 percent from the free-throw line. The Portland Trail Blazers are allowing 36.5 percent shooting from deep and are grabbing 45.5 rebounds per game.

Why the Portland Trail Blazers will win

  • The Pistons have lost each of their last three games as road favorites following a win.
  • The Trail Blazers have won eight of their last 10 games as home underdogs following a win.
  • The Trail Blazers have covered the spread in each of their last 10 games against Central Division opponents following a win.
  • The Pistons have failed to cover the spread in each of their last four games as road favorites.

Why the Detroit Pistons will win

  • The Pistons have won each of their last seven road games against opponents who are on the first leg of a back-to-back.
  • The Trail Blazers have lost nine of their last 10 night games against Eastern Conference opponents that held a winning record.
  • The Pistons have covered the spread in each of their last seven road games against Northwest Division opponents that held a losing record.
  • The Trail Blazers have failed to cover the spread in four of their last five home games on the first leg of a back-to-back.

Total Points Facts

  • Eleven of the Pistons’ last 13 road games on the first leg of a back-to-back have gone UNDER the total points line.
  • Four of the Trail Blazers’ last five games against Central Division opponents have gone UNDER the total points line.

Portland Trail Blazers Player Facts

  • Shaedon Sharpe ranks 6th amongst qualified players for fast break points per game (3.9) this season.
  • Toumani Camara ranks 43rd amongst qualified players for three-pointers made per game (2.4) this season.

Detroit Pistons Player Facts

  • Ausar Thompson rank 14th amongst qualified players for steals + blocks per game (2.3) this season.
  • Tobias Harris ranks 25th amongst qualified Forwards for FT% (82.1%) this season.

Matchup/League Facts

  • The Trail Blazers rank 30th in the league for turnovers per game this season (17.2).
  • The Trail Blazers have recorded the largest comeback win from a Q1 deficit this season – trailed by 20 points vs Thunder on November 5.
  • The Pistons rank 1st for points in the paint per game (57.9) this season.
  • Only 27.6% of the Pistons’ scoring this season has come from beyond the three-point line – lowest mark in the league.

Detroit Pistons vs Portland Trail Blazers Injury Report


The Trail Blazers will be without Damian Lillard, Blake Wesley, Jrue Holiday, Matisse Thybulle, and Scoot Henderson. Jerami Grant is questionable.

Ronald Holland II is questionable for the Pistons.

Detroit Pistons vs Portland Trail Blazers Prediction


The Trail Blazers compete and have games here and there where they surprise. I don’t hate grabbing the points, but I’m rolling with the Pistons. The Pistons are just the more consistent team across the board, and they’re a profitable 16-12 ATS on the year. The Pistons also beat the Trail Blazers a couple of weeks ago by 6 points. Also, the Trail Blazers beat up on the underachieving Warriors and Kings during this winning stretch. That’s not convincing enough. I need to see more. The line is reasonable. Give me the Pistons.

Randy Chambers's Pick: Detroit Pistons -5.5

Hot Cappers

  • Face, Head, Person

    Shane Mickle

    W 47 L 31 +1361 units
    Get Picks
  • Photography, Animal, Canine

    PickDawgz TopDawgz

    W 16 L 9 +696 units
    Get Picks
  • Clothing, Shirt, Face

    Kirk Stuart

    W 17 L 17 +551 units
    Get Picks
  • Clothing, Sleeve, Face

    Brian Bitler

    W 19 L 13 +481 units
    Get Picks
  • Head, Person, Body Part

    Wayne Scott

    W 16 L 13 +322 units
    Get Picks

Latest Picks & Game Previews

  • Coppin State vs Georgetown Prediction 12/22/2025 Today’s College Basketball Picks

    December 22, 2025

  • Bryant vs High Point Prediction 12/22/2025 Today’s College Basketball Picks

    December 22, 2025

  • Eastern Michigan vs Wright State Prediction 12/22/2025 Today’s College Basketball Picks

    December 22, 2025

  • Rider vs VCU Prediction 12/22/2025 Today’s College Basketball Picks

    December 22, 2025

  • Fairleigh Dickinson vs Boston College Prediction 12/22/2025 Today’s College Basketball Picks

    December 22, 2025

  • Prairie View A&M vs LSU Prediction 12/22/2025 Today’s College Basketball Picks

    December 22, 2025

  • St. Louis Blues vs Tampa Bay Lightning Prediction 12/22/2025 Today’s NHL Picks

    December 22, 2025

  • Charlotte Hornets vs Cleveland Cavaliers Prediction 12/22/2025 Today’s NBA Picks

    December 22, 2025

  • Northeastern vs Rhode Island Prediction 12/22/2025 Today’s College Basketball Picks

    December 22, 2025

  • Mississippi Valley State vs West Virginia Prediction 12/22/2025 Today’s College Basketball Picks

    December 22, 2025