Detroit Pistons vs Indiana Pacers Prediction 11/24/2025 Today’s NBA Picks

The Detroit Pistons and the Indiana Pacers collide at the Gainbridge Fieldhouse on Monday night. Here’s a Detroit Pistons vs Indiana Pacers Prediction. This article will include a Detroit Pistons vs Indiana Pacers Pick.

Detroit Pistons Betting Preview 

The Detroit Pistons have been on fire so far this season as they’ve won 14 of their first 16 games. They will be looking to build on their current 12-game win streak after blowing past the Bucks in a 129-116 road win on Saturday. Cade Cunningham led the team with 29 points, eight rebounds and 10 assists on 10 of 18 shooting, Jalen Duren added 19 points with six rebounds and nine assists on seven of 10 shooting while Tobias Harris chipped in with 18 points on seven of nine shooting.

As a team, the Pistons shot a sizzling 63 percent from the field and 16 of 30 from the 3-point line as they took control of the contest with a 39-point explosion in the second quarter to take the early double digit lead. This lead ballooned to 29 points at one stage. 

Indiana Pacers Betting Preview 

Meanwhile, the Indiana Pacers have been in a world of hurt as they’ve lost 14 of their first 16 games and they are hoping to bounce back after getting stopped by the Cavaliers in a 120-109 road defeat on Friday. Andrew Nembhard led the team with 32 points and eight assists on 11 of 20 shooting, Pascal Siakam added 26 points, nine rebounds and four assists on nine of 15 shooting while Bennedict Mathurin chipped in with 21 points.

As a team, the Pacers shot just 42 percent from the field and 11 of 37 from the 3-point line as they showed plenty of fight in the first half to trail by just single digits. Then they allowed 38 points in the third quarter to fall behind by as many as 22 points. 

Why the Indiana Pacers will win

• The Pacers have won nine of their last 10 home games against the Pistons following a road loss.
• The Pistons have lost 32 of their last 40 road games against Central Division opponents.
• The Pacers have covered the spread in five of their last six games against the Pistons following a loss.
• The Pistons have failed to cover the spread in four of their last five road games following a road win.

Why the Detroit Pistons will win

• The Pistons have won each of their last 11 games following a win.
• The Pacers have lost each of their last six games against teams that held a winning record.
• The Pistons have covered the spread in eight of their last nine games against teams that held a losing record.
• The Pacers have failed to cover the spread in four of their last five games when playing with a rest advantage.

Total Points Facts

• Seven of the last eight games between the Pistons and Pacers at Gainbridge Fieldhouse have gone OVER the total points line.
• Five of the Pistons’ last six games against Eastern Conference opponents have gone OVER the total points line.

Indiana Pacers Player Facts

• Bennedict Mathurin leads all Pacers players for points per 36 minutes (28.0) this season.
• T.J. McConnell leads all Pacers players for assists per 36 minutes (8.4) this season.

Detroit Pistons Player Facts

• Isaiah Stewart ranks 2nd amongst qualified players for blocks per game (2.1) this season.
• Ausar Thompson ranks T9th amongst qualified players for steals per game (1.8) this season.

Matchup/League Facts

• The Pacers rank 30th in the league for three-point percentage this season (30.7%).
• The Pacers rank 30th in the league for opponent free throws made per game this season (24.1).
• The Pistons rank 1st for points in the paint per game (59.1) this season.
• Eleven different Pistons players have scored 15+ points in a game this season – equal-most in the league.

Detroit Pistons vs Indiana Pacers Prediction

The Pistons are still missing Marcus Sasser, while the Pacers have ruled out Johnny Furphy, Quenton Jackson, Aaron Nesmith and Obi Toppin again. The Pacers aren’t as bad as their record suggests and they were pretty competitive on Friday against the Cavaliers, but I don’t like their chances against this red-hot Pistons squad. They are racking up the wins at the moment. The Pacers might be able to hang in the contest if Siakam can have another big game, but the Pistons are the tip and I think they can cover this reasonable line with ease.

Peter Tran's Pick: Detroit -9.5