Oct 21, 2025; Oklahoma City, Oklahoma, USA; Houston Rockets center Alperen Sengun (28) drives against Oklahoma City Thunder guard Alex Caruso (9) during overtime at Paycom Center. Mandatory Credit: Alonzo Adams-Imagn Images
Alonzo Adams-Imagn Images

Detroit Pistons vs Houston Rockets Prediction 10/24/2025 Today’s NBA Picks

Pick details

Detroit (0-1) vs Houston (0-1)

October 24, 2025 at 08:00 PM EDT

The Line: Betting Odds: Houston -6 — Over/Under: +226.5

(Get latest betting odds)

The Detroit Pistons invade the Toyota Center to take on the Houston Rockets on Friday night. Here’s a Detroit Pistons vs Houston Rockets Prediction. This article will include a Detroit Pistons vs Houston Rockets Pick.

Detroit Pistons Betting Preview 

The Detroit Pistons will be hoping to avoid a second straight loss after coming up just short to the Bulls in a disappointing 115-111 road defeat on Wednesday night. Cade Cunningham led the team with 23 points, seven rebounds, and 10 assists on eight of 24 shooting. Isaiah Stewart added 20 points, 10 rebounds, and four blocks off the bench. Ronald Holland scored 19 points in 27 minutes, Jalen Duren scored 15 points in 20 minutes of action, while Ausar Thompson tallied 11 points with nine rebounds and seven assists.

As a team, the Pistons shot 44 percent from the field and seven of 24 from the 3-point line as they got off to a terrible start and had to claw their way back from an early 23-point deficit. Only to go cold and score just two points in the final 1:46 to allow the Bulls off the hook in a disappointing finish. Caris LeVert had a quiet game of just eight points off the bench while the newly acquired Duncan Robinson finished with just two points on one of seven shooting. 

Houston Rockets Betting Preview 

Meanwhile, the Houston Rockets will have mixed emotions coming into this one as they fell painfully short to the Thunder in a heartbreaking 125-124 double overtime loss on Tuesday. Alperen Sengun led the team in scoring with 39 points, 11 rebounds, and seven assists on 12 of 24 shooting. Kevin Durant added 23 points with nine rebounds and three assists. Amen Thompson scored 18 points with five assists while Jabari Smith Jr chipped in with 16 points.

As a team, the Rocket shot 44 percent from the field and 11 of 39 from the 3-point line as they stifled the defending champs early on with their tall starting lineup. But in a finish that could’ve gone either way, it was the Thunder’s Shai Gilgeous-Alexander who drained the game-winning free throws with just 2.3 seconds left in the second overtime period. The Rockets will be a little disappointed that they couldn’t get more support from their bench who combined for just 24 points. However, there was a lot to like about their unorthodox starting lineup that didn’t feature a true point guard.

Why the Houston Rockets will win

  • The Rockets have won each of their last 14 night games against teams that held a losing record.
  • The Pistons have lost each of their last five games at Toyota Center following a road loss.
  • The Rockets have covered the spread in seven of their last eight games after coming off overtime.
  • The Pistons have failed to cover the spread in each of their last four games as underdogs when playing with a rest disadvantage.

Why the Detroit Pistons will win

  • The Pistons have won 12 of their last 13 road games against teams that held a losing record.
  • The Rockets have lost each of their last three games when playing with a rest advantage.
  • The Rockets have failed to cover the spread in each of their last six games at Toyota Center when playing with a rest advantage.
  • The Pistons have covered the spread in each of their last six games at Toyota Center following a loss.

Total Points Facts

  • Each of the Rockets’ last four home games against the Pistons following a road loss have gone OVER the total points line.
  • Four of the Pistons’ last five games as underdogs following a road loss have gone UNDER the total points line.

Houston Rockets Player Facts

  • Jabari Smith Jr. has played the most minutes without a turnover (41:45) of any player in the league this season.
  • Alperen Sengun ranks T1st amongst qualified Centers for three-pointers made Per Game (5.0) this season.

Detroit Pistons Player Facts

  • Jalen Duren ranks T4th in the Eastern Conference amongst qualified players for blocks per game (2.0) this season.
  • Tobias Harris ranks T24th amongst qualified players for rebounds per game (9.0) this season.

Matchup/League Facts

  • The Rockets rank 30th in the league for opponent three-point field goal attempts per game this season (52.0).
  • The Rockets rank 30th in the league for opponent field goal attempts per game this season (104.0).
  • The Pistons rank T1st in the league for H2 win percentage this season (100.0%).
  • The Pistons rank T2nd in the league for blocks per game this season (10.0).

Detroit Pistons vs Houston Rockets Prediction

The Pistons are still missing a couple of players, with Jaden Ivey and Marcus Sasser both out, while the Rockets have ruled out Fred VanVleet. They are still keeping eyes on Isaiah Crawford and Jae’Sean Tate, who are both questionable. Both teams are coming into this one fresh off defeats, but at the moment there is more to like about the Rockets, who were really impressive in their narrow defeat to the defending champs in their season opener.

We saw the Rockets’ extra tall starting lineup work pretty well on Tuesday, and I think they can build on that with a better result in this matchup. It wouldn’t be a shock if the Pistons were able to pull off the upset on the road, but I like what I saw from the Rockets. I think they earn their first win of the season in this spot behind a big game from Durant.

Peter Tran's Pick: Houston -6

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