Nov 30, 2025; Cleveland, Ohio, USA; Cleveland Cavaliers guard Donovan Mitchell (45) drives on Boston Celtics forward Xavier Tillman (26) and guard Jordan Walsh (27) during the second half at Rocket Arena. Mandatory Credit: David Dermer-Imagn Images
David Dermer-Imagn Images

Cleveland Cavaliers vs Indiana Pacers Prediction 12/1/2025 Today’s NBA Picks

Pick details

MATCHUP Cleveland Cavaliers Indiana Pacers
Team Records 12-9 4-16
Spread -5.5 -110 +5.5 -110
Moneyline -218 +180
Total Over 233.5 (-115) Under 233.5 (-105)
Where Gainbridge Fieldhouse, Indianapolis, IN
When Monday, December 1, 2025
Time 07:00 PM EST
TV FanDuel SN IN

The Cleveland Cavaliers and the Indiana Pacers collide at the Gainbridge Fieldhouse on Monday night. Here’s a Cleveland Cavaliers vs Indiana Pacers Prediction. This article will include a Cleveland Cavaliers vs Indiana Pacers Pick.

Cleveland Cavaliers Betting Preview 

The Cleveland Cavaliers have cooled off a bit recently as they are now on a three-game losing streak after falling just short to the Celtics in a 117-115 loss last night. Evan Mobley led the team with 27 points, 14 rebounds and four assists on 11 of 17 shooting, Darius Garland added 21 points with eight assists while Donovan Mitchell chipped in with 18 points, seven rebounds and eight assists.

As a team, the Cavaliers shot 46 percent from the field and 20 of 52 from the 3-point line as they got off to a slow start and struggled to keep pace with the Celtics, falling behind by as many as 21 points. This proved to be just enough to hold off the Cavaliers who cut their lead to just one point with 1.2 seconds left in the game. 

Indiana Pacers Betting Preview 

Meanwhile, the Indiana Pacers look to be turning the corner as they are now aiming for a season-high third straight victory after outlasting the Bulls in a 103-101 win on Saturday. Pascal Siakam led the team with 24 points, nine rebounds and four assists on 11 of 23 shooting, Bennedict Mathurin added 19 points while Jay Huff and Andrew Nembhard each scored 14 points.

As a team, the Pacers shot 46 percent from the field and 13 of 41 from the 3-point line as they looked headed for trouble after squandering an 11-point lead to fall behind by seven points late in the fourth quarter. Before the Pacers closed the final 4:29 on a 13-4 run to pull off their second straight win.

Why the Indiana Pacers will win

  • The Cavaliers have lost 10 of their last 11 games at Gainbridge Fieldhouse when playing with a rest disadvantage.
  • The underdogs have won four of the last six games between the Cavaliers and Pacers.
  • The Cavaliers have failed to cover the spread in each of their last seven games when playing with a rest disadvantage.
  • The Pacers have covered the spread in each of their last six games against Eastern Conference opponents.

Why the Cleveland Cavaliers will win

  • The Cavaliers have won 26 of their last 27 night games against Central Division opponents that held a losing record.
  • The Pacers have lost each of their last seven games when playing with a rest advantage.
  • The Cavaliers have covered the spread in six of their last seven road games against Central Division opponents following a loss.
  • The Pacers have failed to cover the spread in six of their last seven home games against Central Division opponents after winning as underdogs.

Total Points Facts

  • Each of the Pacers’ last six games as home underdogs following a home win have gone UNDER the total points line.
  • Five of the Cavaliers’ last six games as favorites have gone UNDER the total points line.

Matchup/League Facts

  • The Pacers rank 30th in the league for opponent free throw attempts per game this season (30.0).
  • The Pacers rank 30th in the league for Q1 points per game this season (26.5).
  • The Cavaliers rank 2nd in the league for H2 points per game this season (60.6).
  • The Cavaliers rank 2nd in the league for Q3 win percentage this season (70.0%).

Cleveland Cavaliers vs Indiana Pacers Prediction

The Cavaliers are still missing Sam Merrill, Max Strus, Lonzo Ball and Jarrett Allen, while the Pacers have ruled out Tyrese Haliburton, Obi Toppin, Aaron Nesmith and Johnny Furphy once again. The Cavaliers haven’t been at their best lately as they’ve been dealing with injuries and they are playing their second game of a back to back set following last night’s tough loss to the Celtics.

The Pacers were absolutely ice-cold for a while there, but they are starting to turn things around with a couple solid wins in a row. I might be tempted to take the Pacers if the bookies were giving us more points. But even though the Cavaliers are playing on zero days rest, I think they bounce back with a win and cover at this modest line.

Peter Tran's Pick: Cleveland -5.5

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