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Jacksonville Jaguars vs Buffalo Bills Prediction NFL Picks 9/23/24

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Buffalo Bills (2-0) vs Jacksonville Jaguars (0-1)

September 23, 2024 at 07:30 PM EDT

The Line: Betting Odds: Buffalo Bills -5.5 / Jacksonville Jaguars +5.5 — Over/Under: 45

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The Jacksonville Jaguars and Buffalo Bills meet Monday in week 3 NFL action at Highmark Stadium. Here’s a Jacksonville Jaguars vs Buffalo Bills Prediction. This article will include a Jacksonville Jaguars vs Buffalo Bills Pick.

Jacksonville Jaguars Betting Preview

The Jacksonville Jaguars lost to the Dolphins and Browns, and they play the Texans next. The Jacksonville Jaguars look to avoid their first 0-3 start since the 2021 season. Trevor Lawrence is completing 51 percent of his passes for 382 yards, 1 touchdown, and 0 interceptions. Brian Thomas Jr. and Gabe Davis have combined for 246 receiving yards and 1 touchdown, while Brenton Strange has 3 receptions.

The Jacksonville Jaguars ground game is averaging 127.5 yards per contest, and Travis Etienne Jr. leads the way with 96 yards and 2 touchdowns. Defensively, Jacksonville is allowing 19 points and 348.5 yards per game. Foyesade Oluokun leads the Jacksonville Jaguars with 19 tackles, Travon Walker has 2 sacks and Josh Hines-Allen has 2 pass deflections.

Buffalo Bills Betting Preview

The Buffalo Bills beat the Cardinals and Dolphins, and they play the Ravens next. The Bills look for their first 3-0 start since the 2020 season. Josh Allen is completing 73.8 percent of his passes for 371 yards, 3 touchdowns, and 0 interceptions. Khalil Shakir and Keon Coleman have combined for 147 receiving yards and 1 touchdown, while James Cook has 4 receptions.

The Buffalo Bills ground game is averaging 119 yards per contest, and Cook leads the way with 149 yards and 2 touchdowns. Defensively, Buffalo is allowing 19 points and 310.5 yards per game. Dorian Williams leads the Buffalo Bills with 19 tackles, Greg Rousseau has 3 sacks and Ja’Marcus Ingram has 2 interceptions.

Why the Buffalo Bills will win

  • The Bills have won each of their last 10 games at Highmark Stadium against opponents on a losing streak.
  • The Jaguars have lost each of their last 11 games as road underdogs following a home loss.
  • The Jaguars have failed to cover the spread in five of their last six games against AFC opponents.
  • The Bills have covered the spread in four of their last five Week 3 games at Highmark Stadium.
  • The Jaguars have lost the first quarter in five of their last six games at Highmark Stadium.
  • The Jaguars have lost the first half in four of their last five games against AFC opponents.

Buffalo Bills Player Prop Facts

  • Josh Allen has scored two touchdowns in three of the Bills’ last four home games.
  • Josh Allen has scored at least one touchdown in seven of the Bills’ last eight home games.
  • Dawson Knox has recorded 15+ receiving yards in each of his six previous regular-season appearances with the Bills as favorites against AFC South opponents.
  • Josh Allen has recorded 248+ passing yards in seven of the Bills’ last eight games as favorites against AFC South opponents.
  • Curtis Samuel has recorded 25+ rushing and receiving yards in nine of his last 10 appearances with his team as a favorite following a win.
  • James Cook has recorded 61+ rushing yards in eight of the Bills’ last nine home games.
  • Josh Allen has recorded 23+ completions in seven of the Bills’ last eight September games as home favorites.
  • Josh Allen has thrown two or more touchdowns in seven of the Bills’ last eight games against AFC South opponents.
  • Rasul Douglas is just one away from 20 career interceptions.

Jacksonville Jaguars Player Prop Facts

  • Travis Etienne has scored at least one touchdown in each of the Jaguars’ last three games following a loss.
  • Trevor Lawrence has recorded 29+ rushing yards in three of his last four appearances following a loss.
  • Christian Kirk has recorded 70+ receiving yards in five of his six previous September appearances with his team as an underdog against AFC opponents.
  • Trevor Lawrence has recorded 264+ passing yards in four of the Jaguars’ last five games as moderate underdogs (+3.5 to +7.0 points).
  • Christian Kirk has recorded 70+ rushing and receiving yards in five of his last six September appearances with his team as an underdog.
  • Trevor Lawrence has recorded 25+ completions in four of the Jaguars’ last five games as moderate underdogs (+3.5 to +7.0 points).
  • Montaric Brown has recorded the equal-most solo tackles in a single game this season (11 vs Browns, Week 2).

Matchup/League Facts

  • The Bills rank T1st in the NFL in H2 points per game (15.5) this season.
  • The Bills rank T1st in the NFL in Q3 win percentage (100.0) this season.
  • The Jaguars rank T29th in the NFL in H2 points per game (5.0) this season.
  • The Jaguars rank T4th in the NFL in Q4 win percentage (50.0) this season.

Jacksonville Jaguars vs Buffalo Bills Prediction

The Jacksonville Jaguars could easily be 2-0 on the season but have come up short thanks to turnovers, penalties, and sloppy play overall. The Jags have shot themselves in the foot twice, and it’s hard to believe things will change on the road against a decent team. The Jaguars also have a poor offensive line, and this physical Bills defense isn’t going to let up. I just don’t believe in the Jaguars based on what we’ve seen through two games. The Bills also have had extra time to prepare for this game after playing last Thursday. Give me the Bills by a touchdown.

Randy Chambers's Pick: Buffalo Bills -5.5

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