Los Angeles Angels vs St. Louis Cardinals Prediction 3/31/25 MLB Picks

In this article, we will formulate a Los Angeles Angels vs St. Louis Cardinals Prediction for this MLB game on Monday, March 31st, at the Busch Stadium. To formulate this prediction, we will look at: 

-The Angels’ recent form and recent player performance 

-The Cardinals’ recent form and recent player performance

-Recent Betting trends and streaks involving Los Angeles

-Recent Betting trends and streaks involving St Louis

-Recent betting trends in games played between LA and St. Louis

-A summary that ties it all together produces a favorable betting outcome for Today’s Game between the Angels and Cardinals. 

What a Start for the Cardinals

It’s been quite the start for the St. Louis Cardinals, and they have won each of the first three games. On Sunday, the Cardinals scored nine runs, including five in the third inning, and they ended up cruising to the win. Nolan Gorman, Pedro Pages, and Victor Scott III all hit a home run. Pages and Scott II all drove in three RBIs. In the first three games of the season, the Cardinals gave up only six runs total against the Minnesota Twins, and they will need the pitching to step up again here. 

Miles Mikolas will start for the Cardinals in this game. He will need to have a strong season. In 2024, he finished with a 10-11 record and an ERA of 5.35. The biggest issue was inconsistency. 

Why the Cardinals Will Beat the Angels

• The Angels have lost each of their last seven night games following a road win.
• The Cardinals have won each of their last five home games.
• The Angels have failed to cover the run line in each of their last eight games following a road win.
• The Cardinals have covered the run line in eight of their last nine games.
• The Cardinals have led after 3 innings in three of their last four games.
• The Cardinals have led after 5 innings in three of their last four night games.

Angels Offense Has to Get Going

The Angels’ offense has to find a way to get going, and even though they have a 2-1 record, the offense just hasn’t been good enough to sustain long-term winning. On Saturday, the Angels secured the 1-0 victory, and on Sunday, they picked up the 3-1 victory over the White Sox. On Sunday, Kyren Parris hit a late home run, and that was enough for the win. Outside of the first game, the pitching was good, and they will probably need to lean on that all year if they want to make the playoffs. 

Tyler Anderson is going to get the start for the Angels, and don’t let the record last year fool you, he was good. Anderson finished with a 10-15 record and an ERA of 3.51. Mike Trout has only one hit in 11 attempts, and they need to get him going. The Angels will face the Guardians following this series.

Why the Angels Will Beat the Cardinals

• The underdogs have won six of the Cardinals’ last seven games.
• The Cardinals have lost three of their last four games as favorites against AL West opponents following a home win.
• The underdogs have covered the run line in each of the Cardinals’ last seven games at Busch Stadium.
• The Cardinals have failed to cover the run line in each of their last five night games against AL West opponents following a win.
• The Cardinals have trailed after 5 innings in three of their last four games against AL West opponents that held a winning record.

Los Angeles Angels vs St. Louis Cardinals Prediction

This game will be all about the pitching for both teams and the lack of quality at-bats for the Angels. The Angels’ bats have been ice cold heading into this game, and the lack of scoring is going to be a major problem again here. Mike Trout looked lost at the plate, and it wouldn’t have been shocking if they had sat him down for this game. If he plays, though, he’s not going to get anything. I also trust Tyler Anderson, and he’s going to have a dominant start here. The Cardinals’ offense will also struggle, and this game will end up under the total. 

Shane Mickle's Pick: Under