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Houston Astros vs Milwaukee Brewers Prediction 5/7/25 MLB Picks

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Milwaukee Brewers (19-18) vs Houston Astros (17-18)

Game Info: Wednesday, May 7, 2025 at 1:10 pm (American Family Field)

The Line: Betting Odds: Milwaukee Brewers +110 / Houston Astros -130 — Over/Under: 7.5

(Get latest betting odds)

The Houston Astros and the Milwaukee Brewers meet Wednesday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs. Milwaukee Brewers prediction.

Starting Pitching Matchup

The Houston Astros will send out Framber Valdez for the start here, and Valdez is 1-4 with a 4.39 ERA and 37 strikeouts this season. This will be Valdez’s first career start against the Brewers. The Milwaukee Brewers will start Quinn Priester here, and Priester is 1-0 with a 5.79 ERA and 17 strikeouts this season. This will be Priester’s first career start against the Astros.

Houston Astros Recap

The Houston Astros come into this game looking to bounce back from their 4-3 loss at the hands of the Brewers in Tuesday’s matchup to improve to 17-18 on the year. After this series, the Astros will head home for an interleague series against the Cincinnati Reds.

Astros Lose 5 Of Their Last 6 Games

Jose Altuve has 35 hits, including 4 home runs and 14 RBIs. Jeremy Pena also has 36 hits with 4 homers and 12 RBIs with 5 stolen bases, while Yordan Alvarez has 4 doubles and a team-high 18 RBIs with 21 strikeouts as well. Jake Meyers has 5 doubles as well, and Christian Walker has also accrued a team-high 40 strikeouts so far this season. Altuve also has 3 stolen bases, while Jake Meyers has a team-high 7 stolen bases this season. Isaac Paredes also has a team-high 4 home runs with 14 RBIs of his own, and Cam Smith has contributed 3 homers and 10 RBIs.

Why the Houston Astros will win

Houston Astros Player Prop Facts

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to add on to their win over the Astros from Tuesday’s matchup to improve their record to 19-18 on the year. After this series, the Brewers will head out on the road for an interleague series against the Tampa Bay Rays.

Brewers Win Third In A Row

Brice Turang has a team-high 41 hits with 3 home runs, 16 RBIs, and 8 stolen bases, while Jackson Chourio has 39 hits with a team-high 12 doubles, 6 home runs, and 24 RBIs, and Sal Frelick has 35 hits as well as 2 triples and 7 stolen bases so far this season. Christian Yelich also has 7 stolen bases with 6 homers and 25 RBIs while also adding 3 doubles. Yelich also has a team-high 38 strikeouts up to this point in the year. William Contreras has 3 homers and 19 RBIs as well this season.

Why the Milwaukee Brewers will win

Milwaukee Brewers Player Prop Facts

Total Runs Facts

Houston Astros vs. Milwaukee Brewers Prediction

I’m on the Astros in this one. I get the case to be made for the Brew Crew, as Milwaukee’s been the better team so far in this series. However, the Astros have a clear edge in starting pitching in this game, and I think Valdez can put the Astros in a spot to salvage something from this series. Give me the Astros in this one.

Chris Ruffolo's Pick: Houston Astros -130

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