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Chicago White Sox vs Kansas City Royals Prediction 5/5/25 MLB Picks

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Kansas City Royals (19-16) vs Chicago White Sox (10-24)

Game Info: Monday, May 5, 2025 at 7:40 pm (Kauffman Stadium)

The Line: Betting Odds: Kansas City Royals -245 / Chicago White Sox +200 — Over/Under: 8

(Get latest betting odds)

The Chicago White Sox and Kansas City Royals meet Monday in MLB action at Kauffman Stadium. Here’s a Chicago White Sox vs Kansas City Royals Prediction. This article will include a Chicago White Sox vs Kansas City Royals Pick.

Chicago White Sox Betting Preview

The Chicago White Sox are 10-24 on the year and play the Marlins, Reds, and Cubs next. The Chicago White Sox are batting .216 on the season, have a .297 OBP, and a .328 slugging percentage. The Chicago White Sox pitching staff has a 4.16 ERA and a 1.37 WHIP. Lenyn Sosa leads the Chicago White Sox with 30 hits and 10 RBI, while Miguel Vargas and Luis Robert Jr. have combined for 48 hits and 27 RBI. 

Shane Smith gets the ball for the Chicago White Sox, and he is 1-1 with a 2.23 ERA and 26 strikeouts this season. This will be Smith’s first career game against the Kansas City Royals.

Kansas City Royals Betting Preview

The Kansas City Royals are 19-16 on the year and play the Red Sox, Astros, and Cardinals next. The Kansas City Royals are batting .237 on the season, have a .297 OBP, and a .360 slugging percentage. The Kansas City Royals pitching staff has a 3.16 ERA and a 1.20 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 41 hits and 17 RBI while Maikel Garcia and Salvador Perez have combined for 68 hits and 30 RBI.

Cole Ragans gets the ball for the Kansas City Royals, and he is 1-1 with a 4.40 ERA and 46 strikeouts this season. Ragans is 1-0 with a 0.00 ERA and 10 strikeouts in his career against the Chicago White Sox.

Why the Kansas City Royals will win

Why the Chicago White Sox will win

Kansas City Royals Player Prop Facts

Chicago White Sox Player Prop Facts

Chicago White Sox vs Kansas City Royals Prediction

The White Sox have cashed some nice underdog tickets recently, but it’s still not enough to have me looking in their direction. The White Sox have been the worst team in baseball these last two years, and they’re 14 games below a .500 record this year. The White Sox do nothing well on either side of the ball, and three wins in their last four games don’t change much. The Royals have caught fire these last couple of weeks, and Ragans misses bats at an elite level. As I’ve said before, I have no use for the White Sox. Give me the Royals and the RL for max betting value.

Randy Chambers's Pick: Kansas City Royals -1.5

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