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Astros vs Phillies Prediction 9/10/2026 Today’s MLB Picks

Apr 1, 2026; Houston, Texas, USA; Houston Astros designated hitter Yordan Alvarez (44) hits a double against the Boston Red Sox during the third inning at Daikin Park. Mandatory Credit: Erik Williams-Imagn Images

Apr 1, 2026; Houston, Texas, USA; Houston Astros designated hitter Yordan Alvarez (44) hits a double against the Boston Red Sox during the third inning at Daikin Park. Mandatory Credit: Erik Williams-Imagn Images

MATCHUP Houston Astros Philadelphia Phillies
Team Records 74-72 82-64
Spread +1.5 -136 -1.5 113
Moneyline +157 -191
Total Over 8.5 (-112) Under 8.5 (-107)
Where Citizens Bank Park, Philadelphia, Pennsylvania
When Thursday, September 10, 2026
Time 01:05 PM EDT
TV MLB.TV
In this article we will formulate an Astros vs Phillies prediction for this MLB game on Thursday, September 10th at Citizens Bank Park in Philadelphia, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Houston Astros Betting Preview

The Houston Astros are 74-72 this year after they split the first two games by scores of 6-5 and 7-11. In game two, Houston led 6-4 in the fourth inning, but they allowed the next seven runs for the loss. The Astros recorded 12 hits and they committed two errors in the game, while they were led by Paredes, who went 2-4 with one home run and three RBIs. Brown allowed seven hits and four earned runs over 5.0 innings, while King picked up the loss. Prior to this series, Houston lost two out of three against the Diamondbacks, but did win three out of four against the White Sox before that. 

This season, Houston has a 4.55 ERA with a 1.35 WHIP and a .239 opponent batting average, while they have scored 660 runs with a .241 batting average and a .315 on base percentage. Yordan Alvarez has led the Astros with 38 home runs and 96 RBIs, while Christian Walker has added 25 home runs and 80 RBIs. The projected starting pitcher for Houston is Cristian Javier, who is 2-5 with a 5.98 ERA and a 1.55 WHIP over 49.2 innings pitched this year. 

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 82-64 this season after they won game two by a score of 11-7 on Wednesday. Philadelphia had their lead cut to 11-7 in the seventh inning, but they closed it down for the win. The Phillies recorded 12 hits and they committed two errors in the game, while they were led by Schwarber, who went 1-5 with one home run and four RBIs. Sanchez allowed 10 hits and six earned runs over 6.0 innings for the win, while Bowlan allowed one earned run in relief. Prior to this series, Philadelphia split four games with the Braves and won two out of three against the Diamondbacks. 

This season, Philadelphia has a 4.00 ERA with a 1.27 WHIP and a .245 opponent batting average, while they have scored 658 runs with a .243 batting average and a .312 on base percentage. Kyle Schwarber has led the Phillies with 44 home runs and 92 RBIs, while Bryce Harper has added 27 home runs and 82 RBIs. The projected starting pitcher for Philadelphia is Zack Wheeler, who is 12-5 with a 3.23 ERA and a 1.08 WHIP over 136.1 innings pitched this season. 

Why the Philadelphia Phillies will win

Why the Houston Astros will win

Total Runs Facts

Philadelphia Phillies Player Prop Facts

Houston Astros Player Prop Facts

Matchup/League Facts

Astros vs Phillies Prediction 

Houston comes into this matchup after losing three of their last four games, but they have scored 13 runs in the first two games of this series. The Astros are 37-34 on the road this year, while the Phillies are 41-33 at home. Philadelphia has alternated wins and losses over their last five games and they have allowed 5+ runs in three of their last four. The Phillies are starting Wheeler, who has allowed two earned runs or fewer in three of his last four starts, while Javier has allowed 3+ earned runs in three of his last five outings. Take the Phillies -1.5 here.

David Racey's Pick: Phillies -1.5

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