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Seattle Seahawks vs Carolina Panthers Prediction 12/28/2025 Today’s NFL Picks

Sep 24, 2023; Seattle, Washington, USA; Seattle Seahawks running back Zach Charbonnet (26) rushes against the Carolina Panthers during the fourth quarter at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

Sep 24, 2023; Seattle, Washington, USA; Seattle Seahawks running back Zach Charbonnet (26) rushes against the Carolina Panthers during the fourth quarter at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

MATCHUP Seattle Seahawks Carolina Panthers
Team Records 12-3 8-7
Spread -7 -118 +7 -102
Moneyline -375 +295
Total Over 42.5 (-110) Under 42.5 (-110)
Where Bank of America Stadium, Charlotte, NC
When Sunday, December 28, 2025
Time 01:00 PM EST
TV CBS
In this article, we will formulate a Seahawks vs Panthers Prediction for this NFL Week 17 game on Sunday, December 28th. Let’s take a look at the prediction for this NFL matchup.

Carolina Panthers Preview


The Carolina Panthers have an 8-7 record this season and are sitting first in the NFC South. They are 9-6 ATS, 7-8 in Over/Under and have a 5-2 home record and a 3-5 away record. The Panthers are coming off a 23-20 home win against the Tampa Bay Buccaneers and will face the Buccaneers next.

Offensively, the Panthers average 19.1 points per game, ranking 27th in the NFL, while defensively, they allow 22.5 points per game, which is 14th. Carolina averages 306.7 total yards per game (182.8 passing and 123.9 rushing), while allowing 329.1 total yards per game (119.5 rushing and 209.6 passing).

Bryce Young leads the Panthers with 2691 passing yards with 63.5% completed passes and 21 touchdowns. Rico Dowdle leads the team in rushing yards with 1007, while Tetairoa McMillan has a team-high 65 receptions for 924 receiving yards, and seven touchdowns. Defensively, Christian Rozeboom has a team-high 105 total tackles (49 of them solo), while Derrick Brown leads the team in sacks, with 5, while Jaycee Horn has a team-high 5 interceptions.

Seattle Seahawks Preview


The Seattle Seahawks have a 12-3 record this season and are sitting first in the NFC West. They are 10-5 ATS, 9-6 in Over/Under and have a 6-2 home record and a 6-1 away record. The Seahawks are coming off a 38-37 home win against the Los Angeles Rams and will face the 49ers next.

Offensively, the Seahawks average 29.5 points per game, ranking 3rd in the NFL, while defensively, they allow 18.6 points per game, which is 2nd. Seattle averages 354.9 total yards per game (238.1 passing and 116.9 rushing), while allowing 303.2 total yards per game (94.1 rushing and 209.1 passing).

Sam Darnold leads the Seahawks with 3703 passing yards with 67.2% completed passes and 24 touchdowns. Kenneth Walker III leads the team in rushing yards with 879, while Jaxon Smith-Njigba has a team-high 104 receptions for 1637 receiving yards, and 10 touchdowns. Defensively, Ernest Jones has a team-high 116 total tackles (57 of them solo), while Byron Murphy and Leonard Williams each lead the team in sacks, with 7 each, while Ernest Jones has a team-high 5 interceptions.

Seattle Seahawks @ Carolina Panthers Betting Trends: Week 17


Why the Carolina Panthers will win

Why the Seattle Seahawks will win

Total Points Facts

Carolina Panthers Player Prop Facts

Seattle Seahawks Player Prop Facts

Matchup/League Facts

Seahawks vs Panthers Prediction


In this Seahawks vs Panthers Prediction, the Seahawks are coming as -7-point road favorites. The Seahawks have a better overall record and have been  almost perfect on the road, having more road wins than the Panthers have at home. They have been red-hot lately, with a 9-1 record in their last 10 games and 6-3 against the spread in their last 9, while the Panthers have been up and down lately, as their offense is struggling to find a rhythm. Seattle is a top-3 squad both offensively and defensibly this season, with a +10.9 point differential and are going up against the league’s fourth-worst offense in Carolina. Take the Seahawks and lay the points on the road in this one.

Nikos Lagouretos's Pick: Seattle Seahawks -7

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