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Detroit Lions vs Cincinnati Bengals Prediction 10/5/2025 Today’s NFL Picks

Sep 29, 2025; Denver, Colorado, USA; Cincinnati Bengals wide receiver Ja'Marr Chase (1) looks on after the game against the Denver Broncos at Empower Field at Mile High. Mandatory Credit: Isaiah J. Downing-Imagn Images

Sep 29, 2025; Denver, Colorado, USA; Cincinnati Bengals wide receiver Ja'Marr Chase (1) looks on after the game against the Denver Broncos at Empower Field at Mile High. Mandatory Credit: Isaiah J. Downing-Imagn Images

MATCHUP Detroit Lions Cincinnati Bengals
Team Records 4-1 2-3
Where Paycor Stadium, Cincinnati, OH
When Sunday, October 5, 2025
Time 04:25 PM EDT
TV FOX
The Detroit Lions and Cincinnati Bengals meet Sunday in NFL action at Paycor Stadium. Here’s a Detroit Lions vs Cincinnati Bengals Prediction. This article will include a Detroit Lions vs Cincinnati Bengals Pick.

Detroit Lions Betting Preview


The Detroit Lions beat the Ravens and Browns, and play the Chiefs next. The Detroit Lions have won 6 of their last 7 regular season games. Jared Goff is completing 73.8 percent of his passes for 929 yards, 9 touchdowns, and 2 interceptions. Amon-Ra St. Brown and Jameson Williams have combined for 521 receiving yards and 7 touchdowns, while Sam LaPorta has 16 receptions.

The Detroit Lions ground game is averaging 139 yards per contest, and Jahmyr Gibbs leads the way with 271 yards and 4 touchdowns. Defensively, Detroit is allowing 22 points and 293 yards per game. Jack Campbell leads the Detroit Lions with 37 tackles, Aidan Hutchinson has 4 sacks and Kerby Joseph has 2 interceptions.

Cincinnati Bengals Betting Preview


The Cincinnati Bengals lost to the Vikings and Broncos, and they play the Packers next. The Cincinnati Bengals have won 7 of their last 9 games. Jake Browning is completing 64.3 percent of his passes for 506 yards, 3 touchdowns, and 5 interceptions. Ja’Marr Chase and Tee Higgins have combined for 400 receiving yards and 2 touchdowns, while Noah Fant has 12 receptions.

The Cincinnati Bengals ground game is averaging 50 yards per contest, and Chase Brown leads the way with 133 yards and 1 touchdown. Defensively, Cincinnati is allowing 29.8 points and 397.8 yards per game. Jordan Battle leads the Cincinnati Bengals with 32 tackles, Trey Hendrickson has 2 sacks and DJ Turner II has 1 interception.

Detroit Lions @ Cincinnati Bengals Betting Trends: Week 5


Why the Cincinnati Bengals will win

Why the Detroit Lions will win

Total Points Facts

Cincinnati Bengals Player Prop Facts

Detroit Lions Player Prop Facts

Matchup/League Facts

Detroit Lions vs Cincinnati Bengals Prediction


This is a thick line for a road team, but the Lions offense that’s first in scoring should have a field day against this Bengals’ defense that looks like last year’s squad. The Bengals can’t get stops, and the offense is extremely limited with Browning at quarterback. Chase was losing it on the sidelines in their last effort. The Bengals also have less time to prepare, which doesn’t help. The Lions have covered 5 of their last 6 games as a favorite. The Bengals have failed to cover 8 of their last 12 games as an underdog. This has the potential to get ugly. Even on the road, give me the Lions in a double-digit victory.

Randy Chambers's Pick: Detroit Lions -8.5

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