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Philadelphia 76ers vs New York Knicks Prediction 10/20/2026 Today’s NBA Picks

Oct 5, 2026; Philadelphia, Pennsylvania, USA; Philadelphia 76ers guard Kentavious Caldwell-Pope (1) controls the ball against New York Knicks guard Jordan Clarkson (00) during the second quarter at Xfinity Mobile Arena. Mandatory Credit: Bill Streicher-Imagn Images

Oct 5, 2026; Philadelphia, Pennsylvania, USA; Philadelphia 76ers guard Kentavious Caldwell-Pope (1) controls the ball against New York Knicks guard Jordan Clarkson (00) during the second quarter at Xfinity Mobile Arena. Mandatory Credit: Bill Streicher-Imagn Images

MATCHUP Philadelphia 76ers New York Knicks
Team Records 1-3 1-4
Spread +4.5 -108 -4.5 -112
Moneyline +150 -180
Total Over 232.5 (-105) Under 232.5 (-115)
Where Madison Square Garden, New York, NY
When Tuesday, October 20, 2026
Time 07:00 PM EDT
TV NBC
The Philadelphia 76ers and New York Knicks meet Tuesday in NBA action at Madison Square Garden. Here’s a Philadelphia 76ers vs. New York Knicks Prediction. This article will include a Philadelphia 76ers vs. New York Knicks pick.

Philadelphia 76ers Betting Preview


The 76ers have made the playoffs in 8 of their last 9 seasons and enter year four under coach Nick Nurse.

The 76ers went from a cute playoff team to a legit title contender with the additions of Jaylen Brown and LeBron James. Add them to Tyrese Maxey, VJ Edgecombe, and Joel Embiid, and Philly has possibly the most talented starting five in the NBA. Kentavious Caldwell-Pope and Anfernee Simons coming off the bench as well is nothing to sneeze at. The 76ers have emerged quickly as a popular title bet in the futures market. The biggest question is fit, as there’s only one ball for guys used to high usage. Also, Embiid has issues staying healthy, and LeBron is 42 years old in December. Still, the talent is there for the 76ers to win their first title since the 80s.

New York Knicks Betting Preview


The Knicks just won their first title since the 70s and enter year two under coach Mike Brown. We’ll see what’s in store for the Knicks in their encore season.

The Knicks bring back their entire core, outside of losing Mitchell Robinson to the Celtics. They replaced him with Andre Drummond. The Knicks are built on chemistry and friendship, and after just winning a title, it’s hard to bet against. The Knicks are the East favorites until proven otherwise, and there’s no reason to get cute with any splashy moves. However, like all teams that just won a chip, motivation could be an issue in the regular season after a long championship run. There’s also now a target on their back, and the East has gotten tougher. Regardless, basketball is alive and well in NYC.

Why the New York Knicks will win

Why the Philadelphia 76ers will win

Total Points Facts

New York Knicks Player Facts

Philadelphia 76ers Player Facts

Matchup/League Facts

Philadelphia 76ers vs New York Knicks Injury Report


The Knicks don’t have any players listed on their injury report.

The 76ers will be without Dominick Barlow, Tacko Fall, and Ariel Hukporti. Adem Bona, Anfernee Simons, and Dean Wade are questionable.

Philadelphia 76ers vs New York Knicks Prediction


You can argue the value is with the 76ers and the points, as they’re one of the more talented teams in the league, and if things break right, they won’t be the underdog often. It’s also Banner Night, which has a history of throwing the champs off. However, the 76ers are a new roster, and it’s going to take time to figure things out. The Knicks have chemistry, and that’s often key early in the season. Also, there’s a lot of hype around the 76ers, and some are already crowning them. That should give the Knicks early motivation to make a statement. I’ll lay the points with the Knicks.

Randy Chambers's Pick: New York Knicks -4.5

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