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Detroit Pistons vs Portland Trail Blazers Prediction 12/22/2025 Today’s NBA Picks

Dec 20, 2025; Detroit, Michigan, USA;  Detroit Pistons guard Jaden Ivey (23) reacts in the second half against the Charlotte Hornets at Little Caesars Arena. Mandatory Credit: Rick Osentoski-Imagn Images

Dec 20, 2025; Detroit, Michigan, USA; Detroit Pistons guard Jaden Ivey (23) reacts in the second half against the Charlotte Hornets at Little Caesars Arena. Mandatory Credit: Rick Osentoski-Imagn Images

MATCHUP Detroit Pistons Portland Trailblazers
Team Records 22-6 12-16
Spread -5.5 -115 +5.5 -105
Moneyline -238 +195
Total Over 234.5 (-115) Under 234.5 (-105)
Where Moda Center, Portland, OR
When Monday, December 22, 2025
Time 10:00 PM EST
TV KUNP 16
The Detroit Pistons and Portland Trail Blazers meet Monday in NBA action at the Moda Center. Here’s a Detroit Pistons vs Portland Trail Blazers Prediction. This article will include a Detroit Pistons vs Portland Trail Blazers Pick.

Detroit Pistons Betting Preview


The Detroit Pistons beat the Hornets, lost to the Mavs, and they play the Kings next. The Pistons have won 20 of their last 24 games.

The Detroit Pistons are averaging 119.4 points on 48.5 percent shooting and allowing 113 points on 44.7 percent shooting. Cade Cunningham is averaging 27.1 points and 6 rebounds, while Jalen Duren is averaging 18 points and 1.7 assists. Tobias Harris is the third double-digit scorer and Duncan Robinson is grabbing 3 rebounds. The Detroit Pistons are shooting 35.6 percent from beyond the arc and 74.8 percent from the free-throw line. The Detroit Pistons are allowing 35.7 percent shooting from deep and are grabbing 46.2 rebounds per game.

Portland Trail Blazers Betting Preview


The Portland Trail Blazers beat the Warriors and Kings, and they play the Magic next. The Trail Blazers have won 3 straight games.

The Portland Trail Blazers are averaging 118.2 points on 44.4 percent shooting and allowing 121.9 points on 48.2 percent shooting. Deni Avdija is averaging 25.5 points and 7.2 rebounds, while Shaedon Sharpe is averaging 21.7 points and 4.6 rebounds. Jerami Grant is the third double-digit scorer and Jrue Holiday is grabbing 5.3 rebounds. The Portland Trail Blazers are shooting 33.5 percent from beyond the arc and 80 percent from the free-throw line. The Portland Trail Blazers are allowing 36.5 percent shooting from deep and are grabbing 45.5 rebounds per game.

Why the Portland Trail Blazers will win

Why the Detroit Pistons will win

Total Points Facts

Portland Trail Blazers Player Facts

Detroit Pistons Player Facts

Matchup/League Facts

Detroit Pistons vs Portland Trail Blazers Injury Report


The Trail Blazers will be without Damian Lillard, Blake Wesley, Jrue Holiday, Matisse Thybulle, and Scoot Henderson. Jerami Grant is questionable.

Ronald Holland II is questionable for the Pistons.

Detroit Pistons vs Portland Trail Blazers Prediction


The Trail Blazers compete and have games here and there where they surprise. I don’t hate grabbing the points, but I’m rolling with the Pistons. The Pistons are just the more consistent team across the board, and they’re a profitable 16-12 ATS on the year. The Pistons also beat the Trail Blazers a couple of weeks ago by 6 points. Also, the Trail Blazers beat up on the underachieving Warriors and Kings during this winning stretch. That’s not convincing enough. I need to see more. The line is reasonable. Give me the Pistons.

Randy Chambers's Pick: Detroit Pistons -5.5

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