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Washington Nationals vs Baltimore Orioles Prediction 5/16/25 MLB Picks

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Baltimore Orioles (15-27) vs Washington Nationals (18-27)

Game Info: Friday, May 16, 2025 at 7:05 pm (Oriole Park at Camden Yards)

The Line: Betting Odds: Baltimore Orioles -115 / Washington Nationals -105 — Over/Under: 9

(Get latest betting odds)

The Washington Nationals and Baltimore Orioles meet Friday in MLB action at Oriole Park at Camden Yards. Here’s a Washington Nationals vs Baltimore Orioles Prediction. This article will include a Washington Nationals vs Baltimore Orioles Pick.

Washington Nationals Betting Preview

The Washington Nationals are 18-27 on the year and play the Braves, Giants, and Mariners next. The Washington Nationals are batting .238 on the season, have a .308 OBP, and a .377 slugging percentage. The Washington Nationals’ pitching staff has a 5.37 ERA and a 1.45 WHIP. James Wood leads the Washington Nationals with 46 hits and 25 RBI, while Keibert Ruiz and CJ Abrams have combined for 81 hits and 30 RBI. 

MacKenzie Gore gets the ball for the Washington Nationals, and he is 2-4 with a 3.59 ERA and 75 strikeouts this season. Gore is 0-2 with a 3.75 ERA and 15 strikeouts in his career against the Baltimore Orioles.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 15-27 on the year and play the Brewers, Red Sox, and Cardinals next. The Baltimore Orioles are batting .226 on the season, have a .295 OBP, and a .381 slugging percentage. The Baltimore Orioles pitching staff has a 5.34 ERA and a 1.48 WHIP. Gunnar Henderson leads the Baltimore Orioles with 38 hits and 12 RBI, while Ryan O’Hearn and Cedric Mullins have combined for 66 hits and 39 RBI.

Cade Povich gets the ball for the Baltimore Orioles, and he is 1-3 with a 5.55 ERA and 29 strikeouts this season. This will be Povich’s second career game against the Washington Nationals.

Why the Baltimore Orioles will win

Why the Washington Nationals will win

Baltimore Orioles Player Prop Facts

Washington Nationals Player Prop Facts

Washington Nationals vs Baltimore Orioles Prediction

I keep saying the Orioles aren’t a good team, and they keep losing games. The Orioles have won six games since April 20. I’m just not excited to get behind the Orioles. I’m even less interested in Povich on the mound, a pitcher who has allowed 43 hits and 22 earned runs in 35.2 innings. In 17 home innings, Povich has a 7.94 ERA and a .300 allowed batting average. The Nationals aren’t playing any better, but they have the edge with Gore on the bump. Gore is first in strikeouts and has a top-40 WHIP at 1.16. Give me the Nationals and the more reasonable price with the better pitcher. 

Randy Chambers's Pick: Washington Nationals -105

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