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Toronto Blue Jays vs Los Angeles Angels Prediction 4/21/2026 Today’s MLB Picks

Apr 18, 2026; Anaheim, California, USA; Los Angeles Angels center fielder Mike Trout (27) runs after hitting a double during the sixth inning against the San Diego Padres at Angel Stadium. Mandatory Credit: William Liang-Imagn Images

Apr 18, 2026; Anaheim, California, USA; Los Angeles Angels center fielder Mike Trout (27) runs after hitting a double during the sixth inning against the San Diego Padres at Angel Stadium. Mandatory Credit: William Liang-Imagn Images

MATCHUP Toronto Blue Jays Los Angeles Angels
Team Records 9-13 11-13
Where Angel Stadium, Anaheim, California
When Tuesday, April 21, 2026
Time 09:38 PM EDT
TV ESPN Unlmtd

The Toronto Blue Jays and the Los Angeles Angels meet Tuesday in MLB action from Angels Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Toronto Blue Jays vs. Los Angeles Angels prediction.

Starting Pitching Matchup

The Toronto Blue Jays will send out Patrick Corbin for the start and Corbin is 0-0 with a 4.66 ERA and 9 strikeouts this season. In his last five starts against the Angels, Corbin is 3-0 with a 2.96 ERA and 28 strikeouts. Jack Kochanowicz will start for the Angels here and is 2-0 with a 3.47 ERA and 18 strikeouts this season. In his career, Kochanowicz is 0-0 with a 4.76 ERA and 2 strikeouts against the Blue Jays.

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to add on to their 5-2 win over the Angels from Monday’s matchup to sit at 9-13 this season. After this series, the Blue Jays will take on the Cleveland Guardians a series at home.

Blue Jays Pick Up Back-To-Back Ws

Going into Monday, Andres Gimenez has 21 hits with 3 doubles, a triple, 3 home runs and 12 RBIs while Ernie Clement has 26 hits with 9 doubles and 5 RBIs. Kazuma Okamoto has 17 hits with 2 doubles, 3 home runs, 8 RBIs and a team-high 29 strikeouts while George Springer also has 4 doubles, 2 homers with 6 RBIs. Vladimir Guerrero Jr. has 26 hits with 5 doubles, a home run and 10 RBIs as well. Jesus Sanchez also has 17 hits with 3 doubles, 2 home runs and 11 RBIs.

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to rebound from their loss at the hands of Toronto last time out to sit at 11-13 on the year. After this series, the Angels will head on the road for a series against the Kansas City Royals.

Angels Lose 3 In A Row

Entering Monday, Nolan Schanuel has 18 hits with 2 doubles, a pair of homers and 13 RBIs while Mike Trout’s added 22 hits with 4 doubles, 7 home runs and 16 RBIs this season. Zach Neto’s also added 22 hits with 5 doubles, 5 homers and 11 RBIs and Jo Adell has 26 hits with 3 home runs and 14 RBIs as well this season. Oswald Peraza has 17 hits with 4 doubles, 4 home runs and 8 RBIs and Jorge Soler has 16 hits with 3 doubles, 5 home runs and 18 RBIs well this season.

Toronto Blue Jays @ Los Angeles Angels Betting Trends: April 21, 2026

Why the Los Angeles Angels will win

Why the Toronto Blue Jays will win

Total Runs Facts

Los Angeles Angels Player Prop Facts

Toronto Blue Jays Player Prop Facts

Matchup/League Facts

Toronto Blue Jays vs. Los Angeles Angels Prediction

I’m on the Blue Jays in this one. I’m not the biggest fan of Patrick Corbin, but he’s been serviceable in his Blue Jays tenure so far and he has really solid numbers against the Angels, who have been struggling as of late. I think the Blue Jays are going on a run and I think that they pick up another win here. Give me Toronto in this one.

Chris Ruffolo's Pick: Toronto +100

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