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St. Louis Cardinals vs Atlanta Braves Prediction 4/21/25 MLB Picks

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Atlanta Braves (8-13) vs St. Louis Cardinals (9-13)

Game Info: Monday, April 21, 2025 at 7:15 pm (Truist Park)

The Line: Betting Odds: Atlanta Braves -192 / St. Louis Cardinals +160 — Over/Under: 8.5

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The St. Louis Cardinals and the Atlanta Braves meet Monday in MLB action from Truist Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a St. Louis Cardinals vs. Atlanta Braves prediction.

Starting Pitching Matchup

The St. Louis Cardinals will send out Erick Fedde for the start here, and Fedde is 1-2 with a 3.43 ERA and 10 strikeouts this season. In his last five starts against Atlanta, Fedde is 0-4 with a 9.00 ERA and 18 strikeouts. Spencer Schwellenbach will get the start for Atlanta here and is 1-1 with a 2.55 ERA and 22 strikeouts this season. In his career, Schwellenbach is 0-2 with a 6.55 ERA and 14 strikeouts against the Cardinals.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to rebound after ending up with a 7-4 loss at the hands of the New York Mets last time out, to fall to 9-13 on the year. After this series, the St. Louis Cardinals will head home for a series against the Milwaukee Brewers.

Cardinals Swept In Four-Game Set Vs. Mets

Brendan Donovan has a team-high 31 hits along with 7 doubles, 3 home runs, and 13 RBIs, while Lars Nootbaar has 20 hits with 3 home runs, 11 RBIs, and a pair of stolen bases. Nolan Arenado also has 21 hits with 6 doubles of his own, and Victor Scott II has 16 hits with a pair of doubles, a triple, 7 RBIs, and a team-high 7 stolen bases. Ivan Herrera’s also added a team-high 4 home runs and 11 RBIs so far this season.

Why the St. Louis Cardinals will win

St. Louis Cardinals Player Prop Facts

Atlanta Braves Recap

The Atlanta Braves come into this game looking to build on their 6-2 win over the Minnesota Twins last time out to improve to 8-13 on the year. After this series, the Braves will head on the road to take on the Arizona Diamondbacks.

Braves Complete Sweep Of Twins

Austin Riley leads the Braves with 23 hits, including 5 home runs, 13 RBIs, and a team-high 4 doubles, but also has the dubious distinction of leading Atlanta with 31 strikeouts so far this season. Ozzie Albies has 20 hits with 4 home runs and 11 RBIs, and Matt Olson has 17 hits with 4 doubles, 3 home runs, and 13 RBIs of his own. Marcell Ozuna also has 18 hits with 4 home runs and 9 RBIs. Michael Harris II also has 16 hits with 3 doubles, 3 home runs, and 9 RBIs, and 4 stolen bases as well, and Nick Allen has a team-high 4 stolen bases this season.

Why the Atlanta Braves will win

Atlanta Braves Player Prop Facts

Total Runs Facts

St. Louis Cardinals vs. Atlanta Braves Prediction

I’m on the Braves here. I get the case to be made for the Cardinals if this game were played in St. Louis, but the Cardinals haven’t been able to keep up their play on the road this season, and I think they could struggle here as well. Schwellenbach is still one of Atlanta’s best, and I think he delivers another strong outing here to get the win for the Braves. Give me Atlanta in this one.

Chris Ruffolo's Pick: Atlanta Braves -192

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