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Seattle Mariners vs Houston Astros Prediction 5/11/2026 Today’s MLB Picks

May 10, 2026; Chicago, Illinois, USA;  Seattle Mariners pitcher Eduard Bazardo (83) after the eighth inning against the Chicago White Sox at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

May 10, 2026; Chicago, Illinois, USA; Seattle Mariners pitcher Eduard Bazardo (83) after the eighth inning against the Chicago White Sox at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Seattle Mariners Houston Astros
Team Records 19-22 16-25
Spread -1.5 119 +1.5 -143
Moneyline -143 +119
Total Over 8.5 (-106) Under 8.5 (-113)
Where Daikin Park, Houston, Texas
When Monday, May 11, 2026
Time 08:10 PM EDT
TV MLB.TV
The Seattle Mariners and Houston Astros meet Monday in MLB action at Daikin Park. Here’s a Seattle Mariners vs. Houston Astros Prediction. This article will include a Seattle Mariners vs. Houston Astros Pick.

Seattle Mariners Betting Preview


The Seattle Mariners are 19-22 on the year and play the White Sox and Padres next. The Seattle Mariners are batting. 229 on the season, have a .319 OBP, and have a .378 slugging percentage. The Seattle Mariners’ pitching staff has a 3.78 ERA and a 1.23 WHIP. Julio Rodriguez leads the Seattle Mariners with 44 hits and 18 RBI while Josh Naylor and Randy Arozarena have combined for 79 hits and 33 RBI.

George Kirby gets the ball for the Seattle Mariners, and he is 4-2 with a 2.94 ERA and 39 strikeouts this season. Kirby is 5-1 with a 2.17 ERA and 54 strikeouts in his career against the Houston Astros.

Houston Astros Betting Preview


The Houston Astros are 16-25 on the year and play the Rangers and Twins next. The Houston Astros are batting. 258 on the season, have a .333 OBP, and have a .429 slugging percentage. The Houston Astros pitching staff has a 5.57 ERA and a 1.60 WHIP. Yordan Alvarez leads the Houston Astros with 48 hits and 29 RBI while Jose Altuve and Christian Walker have combined for 77 hits and 36 RBI.

Peter Lambert gets the ball for the Houston Astros, and he is 2-2 with a 2.42 ERA and 23 strikeouts this season. This will be Lambert’s second career game against the Seattle Mariners.

Why the Houston Astros will win

Why the Seattle Mariners will win

Total Runs Facts

Houston Astros Player Prop Facts

Seattle Mariners Player Prop Facts

Matchup/League Facts

Seattle Mariners vs Houston Astros Prediction


I’m not excited to get behind either of these teams that have underachieved up to this point. The Mariners were a popular World Series pick before the season and they’re three games below a .500 record. The Astros have a losing record at home and their pitching staff has been horrendous. I’m grabbing the under in this spot. Kirby has a 2.94 ERA and 1.10 WHIP through 52 innings, while Lambert has a 2.42 ERA and 1.16 WHIP through 22.1 innings. Lambert has yet to allow a home run this season. Two pitchers in good form, I expect a somewhat low-scoring game. Give me the under.

Randy Chambers's Pick: Under

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