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San Francisco Giants vs Detroit Tigers Prediction 5/26/25 MLB Picks

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Detroit Tigers (34-20) vs San Francisco Giants (31-22)

Game Info: Monday, May 26, 2025 at 1:10 pm (Comerica Park)

The Line: Betting Odds: Detroit Tigers -112 / San Francisco Giants -108 — Over/Under: 8

(Get latest betting odds)

The San Francisco Giants and Detroit Tigers meet Monday in MLB action at Comerica Park. Here’s a San Francisco Giants vs Detroit Tigers Prediction. This article will include a San Francisco Giants vs Detroit Tigers Pick.

San Francisco Giants Betting Preview

The San Francisco Giants are 31-22 on the year and play the Marlins, Padres, and Braves next. The San Francisco Giants are batting .232 on the season, have a .310 OBP, and a .380 slugging percentage. The San Francisco Giants’ pitching staff has a 3.25 ERA and a 1.21 WHIP. Jung Hoo Lee leads the San Francisco Giants with 57 hits and 31 RBI, while Heliot Ramos and Wilmer Flores have combined for 103 hits and 70 RBI. 

Hayden Birdsong gets the ball for the San Francisco Giants, and he is 2-0 with a 1.91 ERA and 29 strikeouts this season. This will be Birdsong’s second career game against the Detroit Tigers.

Detroit Tigers Betting Preview

The Detroit Tigers are 34-20 on the year and play the Royals, White Sox, and Cubs next. The Detroit Tigers are batting .253 on the season, have a .326 OBP, and a .412 slugging percentage. The Detroit Tigers’ pitching staff has a 3.31 ERA and a 1.16 WHIP. Riley Greene leads the Detroit Tigers with 54 hits and 34 RBI, while Kerry Carpenter and Zach McKinstry have combined for 95 hits and 41 RBI.

Keider Montero gets the ball for the Detroit Tigers, and he is 1-1 with a 5.28 ERA and 21 strikeouts this season. This will be Montero’s second career game against the San Francisco Giants.

Why the Detroit Tigers will win

Why the San Francisco Giants will win

Detroit Tigers Player Prop Facts

San Francisco Giants Player Prop Facts

San Francisco Giants vs Detroit Tigers Prediction

The Tigers have cooled off over the last week or so, and they’re throwing out a struggling pitcher in Montero, who has allowed 18 hits and nine runs in his last 17 innings. Montero has an ERA over five on the season, and he has a 5.25 ERA and .292 allowed batting average in 12 home innings. Birdsong has allowed 14 hits and four earned runs in his last 12.1 innings, and just four earned runs in his last 18.1 innings. Birdsong has also increased his workload in recent performances. Never a fan of bullpen games, but the Giants have the edge on Monday. I’ll roll with the road team and the soft price.

Randy Chambers's Pick: San Francisco Giants -108

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