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San Diego Padres vs Seattle Mariners Prediction 5/16/2026 Today’s MLB Picks

May 15, 2026; Seattle, Washington, USA; San Diego Padres shortstop Xander Bogaerts (2) attempts to field a ground ball barehanded during the eighth inning against the Seattle Mariners at T-Mobile Park. Mandatory Credit: Stephen Brashear-Imagn Images

May 15, 2026; Seattle, Washington, USA; San Diego Padres shortstop Xander Bogaerts (2) attempts to field a ground ball barehanded during the eighth inning against the Seattle Mariners at T-Mobile Park. Mandatory Credit: Stephen Brashear-Imagn Images

MATCHUP San Diego Padres Seattle Mariners
Team Records 26-18 22-24
Spread +1.5 -157 -1.5 130
Moneyline +139 -168
Total Over 7 (-119) Under 7 (-102)
Where T-Mobile Park, Seattle, Washington
When Saturday, May 16, 2026
Time 07:15 PM EDT
TV MLB.TV
The San Diego Padres and Seattle Mariners meet Saturday in MLB action at T-Mobile Park. Here’s a San Diego Padres vs. Seattle Mariners Prediction. This article will include a San Diego Padres vs. Seattle Mariners Pick.

San Diego Padres Betting Preview


The San Diego Padres are 26-18 on the year and play the Dodgers and Athletics next. The San Diego Padres are batting. 223 on the season, have a .294 OBP, and have a .363 slugging percentage. The San Diego Padres pitching staff has a 4.04 ERA and a 1.26 WHIP. Xander Bogaerts leads the San Diego Padres with 41 hits and 23 RBI, while Miguel Andujar and Fernando Tatis Jr. have combined for 73 hits and 28 RBI.

Walker Buehler gets the ball for the San Diego Padres, and he is 2-2 with a 5.20 ERA and 31 strikeouts this season. Buehler is 2-1 with a 6.39 ERA and 26 strikeouts in his career against the Seattle Mariners.

Seattle Mariners Betting Preview


The Seattle Mariners are 22-24 on the year and play the White Sox and Royals next. The Seattle Mariners are batting. 232 on the season, have a .321 OBP, and have a .383 slugging percentage. The Seattle Mariners’ pitching staff has a 3.58 ERA and a 1.23 WHIP. Randy Arozarena leads the Seattle Mariners with 51 hits and 16 RBI while Josh Naylor and Julio Rodriguez have combined for 89 hits and 40 RBI.

Logan Gilbert gets the ball for the Seattle Mariners, and he is 2-3 with a 3.76 ERA and 52 strikeouts this season. Gilbert is 4-1 with a 1.69 ERA and 31 strikeouts in his career against the San Diego Padres.

Why the Seattle Mariners will win

Why the San Diego Padres will win

Total Runs Facts

Seattle Mariners Player Prop Facts

San Diego Padres Player Prop Facts

Matchup/League Facts

San Diego Padres vs Seattle Mariners Prediction


You can make a case for the Padres and the plus money based on their team success, but I can’t get there with Buehler on the bump. Through 36.1 innings, Buehler has a 5.20 ERA and 1.35 WHIP with 12 walks. Gilbert has had issues keeping the ball in the park, but through 50 innings, he has a 3.78 ERA and 1.16 WHIP. He’s averaging more than a strikeout per inning. The Mariners have the edge on the mound and they’re usually at their best at home. Give me the M’s and the reasonable price.

Randy Chambers's Pick: Seattle Mariners

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