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San Diego Padres vs Arizona Diamondbacks Prediction 8/5/2026 Today’s MLB Picks

Aug 4, 2026; Phoenix, Arizona, USA; Arizona Diamondbacks third baseman Nolan Arenado hits a two run home run in the seventh inning against the San Diego Padres at Chase Field. Mandatory Credit: Mark J. Rebilas-Imagn Images

Aug 4, 2026; Phoenix, Arizona, USA; Arizona Diamondbacks third baseman Nolan Arenado hits a two run home run in the seventh inning against the San Diego Padres at Chase Field. Mandatory Credit: Mark J. Rebilas-Imagn Images

MATCHUP San Diego Padres Arizona Diamondbacks
Team Records 59-55 60-54
Spread -1.5 135 +1.5 -163
Moneyline -121 +100
Total Over 9 (-122) Under 9 (101)
Where Chase Field, Phoenix, Arizona
When Wednesday, August 5, 2026
Time 09:40 PM EDT
TV MLB.TV
The San Diego Padres and Arizona Diamondbacks meet Wednesday in MLB action at Chase Field. Here’s a San Diego Padres vs Arizona Diamondbacks Prediction. This article will include a San Diego Padres vs Arizona Diamondbacks Pick.

San Diego Padres Betting Preview


The San Diego Padres are 59-55 on the year and play the Astros and Brewers next. The San Diego Padres are batting .236 on the season, have a .312 OBP, and have a .384 slugging percentage. The San Diego Padres’ pitching staff has a 4.15 ERA and a 1.32 WHIP. Fernando Tatis Jr. leads the San Diego Padres with 123 hits and 49 RBI, while Jackson Merrill and Manny Machado have combined for 192 hits and 123 RBI.

Casey Mize gets the ball for the San Diego Padres, and he is 4-6 with a 2.70 ERA and 85 strikeouts this season. Mize is 0-0 with a 2.35 ERA and 11 strikeouts in his career against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview


The Arizona Diamondbacks are 60-54 on the year and play the Dodgers and Rockies next. The Arizona Diamondbacks are batting .241 on the season, have a .314 OBP, and have a .392 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.20 ERA and a 1.30 WHIP. Ketel Marte leads the Arizona Diamondbacks with 109 hits and 62 RBI, while Corbin Carroll and Geraldo Perdomo have combined for 194 hits and 93 RBI.

Mitch Bratt gets the ball for the Arizona Diamondbacks, and he is 0-1 with a 5.23 ERA and 12 strikeouts this season. This will be Bratt’s first career game against the San Diego Padres.

Why the Arizona Diamondbacks will win

Why the San Diego Padres will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

San Diego Padres Player Prop Facts

Matchup/League Facts

San Diego Padres vs Arizona Diamondbacks Prediction


The Padres are having a strong week and look like a team that’s ready to make that playoff push. Mize is an addition that hopes to help, as he had a 2.70 ERA and 0.99 WHIP with the Tigers and is fresh off a July week in which he allowed 7 earned runs in 21.2 innings. Bratt has just 20.2 innings under his belt this season, and he hasn’t been good in those frames. The Padres are showing up offensively and have a pitcher who is dealing and has a new lease on life. Give me the Padres.

Randy Chambers's Pick: San Diego Padres

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