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Pittsburgh Pirates vs Detroit Tigers Prediction 9/25/2026 Today’s MLB Picks

Sep 24, 2026; Pittsburgh, Pennsylvania, USA;  Pittsburgh Pirates right fielder Ronny Simon (63) celebrates in the dugout after scoring a run against the St. Louis Cardinals during the eighth inning at PNC Park.  Mandatory Credit: Charles LeClaire-Imagn Images

Sep 24, 2026; Pittsburgh, Pennsylvania, USA; Pittsburgh Pirates right fielder Ronny Simon (63) celebrates in the dugout after scoring a run against the St. Louis Cardinals during the eighth inning at PNC Park. Mandatory Credit: Charles LeClaire-Imagn Images

MATCHUP Pittsburgh Pirates Detroit Tigers
Team Records 81-78 74-85
Spread -1.5 158 +1.5 -193
Moneyline -109 -110
Total Over 8 (-102) Under 8 (-118)
Where Comerica Park, Detroit, Michigan
When Friday, September 25, 2026
Time 06:40 PM EDT
TV MLB.TV
The Pittsburgh Pirates and Detroit Tigers meet Friday in MLB action at Comerica Park. Here’s a Pittsburgh Pirates vs. Detroit Tigers Prediction. This article will include a Pittsburgh Pirates vs. Detroit Tigers Pick.

Pittsburgh Pirates Betting Preview


The Pittsburgh Pirates are 80-78 this year. The Pittsburgh Pirates are batting .253 on the season, with a .331 OBP and a .404 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 4.15 ERA and a 1.30 WHIP. Nick Gonzales leads the Pittsburgh Pirates with 164 hits and 60 RBI, while Bryan Reynolds and Brandon Lowe have combined for 304 hits and 165 RBI.

Bubba Chandler gets the ball for the Pittsburgh Pirates, and he is 8-9 with a 4.34 ERA and 138 strikeouts this season. This will be Chandler’s first career game against the Detroit Tigers.

Detroit Tigers Betting Preview


The Detroit Tigers are 74-85 on the year. The Detroit Tigers are batting .241 on the season and have a .320 OBP and a .400 slugging percentage. The Detroit Tigers’ pitching staff has a 3.65 ERA and a 1.22 WHIP. Kevin McGonigle leads the Detroit Tigers with 165 hits and 70 RBI, while Dillon Dingler and Riley Greene have combined for 273 hits and 164 RBI.

Jackson Jobe gets the ball for the Detroit Tigers, and he is 2-2 with a 3.98 ERA and 43 strikeouts this season. This will be Jobe’s second career game against the Pittsburgh Pirates.

Why the Detroit Tigers will win

Why the Pittsburgh Pirates will win

Total Runs Facts

Detroit Tigers Player Prop Facts

Pittsburgh Pirates Player Prop Facts

Matchup/League Facts

Pittsburgh Pirates vs Detroit Tigers Prediction


Meaningless game and two subpar pitchers on the mound, but in a pick-em spot, I will lean Pirates because Chandler has a more trustworthy sample size of 151.1 innings. Jobe has pitched just 40.2 innings this season, and at home he has a 5.02 ERA and a .281 batting average allowed. It’s kind of the lesser of the two evils. There are better ways to spend your Friday night, but if forced to pick, I’d lean toward the Pirates and the pitcher with the larger sample size.

Randy Chambers's Pick: Pittsburgh Pirates

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