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Philadelphia Phillies vs Washington Nationals Prediction 3/29/25 MLB Picks

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Washington Nationals (0-1) vs Philadelphia Phillies (1-0)

Game Info: Saturday, March 29, 2025 at 4:05 pm (Nationals Park)

The Line: Betting Odds: Washington Nationals +136 / Philadelphia Phillies -162 — Over/Under: 8.5

(Get latest betting odds)

The Philadelphia Phillies and the Washington Nationals meet on Saturday in MLB action from Nationals Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Philadelphia Phillies vs. Washington Nationals prediction.

Starting Pitching Matchup

The Philadelphia Phillies will start Jesus Luzardo here, and Luzardo was 3-6 with a 5.00 ERA and 58 strikeouts last season. In his last five starts against Washington, Luzardo is 1-1 with a 4.00 ERA and 22 strikeouts. Jake Irvin will get the start for Washington here and was 10-14 with a 4.41 ERA and 156 strikeouts last season. In his last five starts against the Phillies, Irvin is 0-3 with a 5.93 ERA and 22 strikeouts.

Philadelphia Phillies Recap

The Philadelphia Phillies will be out to add on to their 7-3 win in extra innings from Thursday’s series and season opener. After this series, the Phillies will head home for their opening series against the Colorado Rockies.

Phillies Looking To Win Series Ahead Of Sunday’s Finale

Alec Bohm and J.T. Realmuto each had two RBIs, with Bohm going 2 for 5 with a double, while Realmuto added a triple. Kyle Schwarber and Bryce Harper each had a solo home run, while Max Kepler added a double. Nick Castellanos also chipped in a base knock as well to cap off the offense for the Phillies in the winning effort. Zack Wheeler allowed one run on two hits with eight strikeouts over six innings of work in the start, not factoring in the decision. Jose Alvarado got the win in relief to improve to 1-0 on the year.

Why the Philadelphia Phillies will win

Philadelphia Phillies Player Prop Facts

Washington Nationals Recap

The Washington Nationals will be looking to bounce back after starting the year on the wrong foot with their loss to the Phils on Thursday. After this series, Washington will head on the road for a series with the Toronto Blue Jays.

Nationals Looking To Even Set Up At One Win Apiece

Keibert Ruiz went 2 for 4 with a solo home run in the loss, while Luis Garcia Jr. went 2 for 4 with an RBI, and CJ Abrams added an RBI as well in the loss. Nathaniel Lowe added a base hit as well to cap off the offense for Washington in the defeat. The rest of the Nationals, including Abrams, who went 0 for 5 at the dish in the loss, went 0 for 21 with 9 strikeouts and went just 2 for 11 with runners in scoring position in the loss. MacKenzie Gore went six innings of one-hit shutout baseball with 13 strikeouts, not factoring in the decision. Colin Poche took the loss in relief, falling to 0-1 on the year as a result.

Why the Washington Nationals will win

Washington Nationals Player Prop Facts

Total Runs Facts

Philadelphia Phillies vs. Washington Nationals Prediction

I’m on the Phillies here. I just think really highly of Jesus Luzardo, as I think he has high-end stuff and is a lefty, so that can be hard to deal with when his stuff is on point. Jake Irvin really had issues with the Phillies last year and really seemed to struggle at home, and I think that comes to fruition once again, despite the calendar flipping to 2025. All in all, I think the Phillies get the win here, so give me Philadelphia in this one.

Chris Ruffolo's Pick: Philadelphia Phillies -162

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