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Philadelphia Phillies vs Pittsburgh Pirates Prediction 6/6/25 MLB Picks

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Pittsburgh Pirates (23-40) vs Philadelphia Phillies (37-25)

Game Info: Friday, June 6, 2025 at 6:40 pm (PNC Park)

The Line: Betting Odds: Pittsburgh Pirates +114 / Philadelphia Phillies -135 — Over/Under: 9

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The Philadelphia Phillies and the Pittsburgh Pirates meet Friday in MLB action from PNC Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Philadelphia Phillies vs. Pittsburgh Pirates prediction.

Starting Pitching Matchup

The Philadelphia Phillies will send out Joe Ross for the start here, and Ross is 2-1 with a 4.34 ERA and 22 strikeouts this season. In his last five starts against Pittsburgh, Ross is 1-2 with a 2.82 ERA and 23 strikeouts. Bailey Falter will get the start for the Pirates and is 4-3 with a 3.14 ERA and 41 strikeouts this season. This will be Falter’s second career start against the Phillies.

Philadelphia Phillies Recap

The Philadelphia Phillies come into this game looking to bounce back from a 9-1 loss at the hands of the Toronto Blue Jays last time out to slip to 37-25 on the year. After this series, the Phillies will head home for a series against the Chicago Cubs.

Phillies Drop 6 Of Their Last 7

Nick Castellanos has 67 hits with 15 doubles, including 6 home runs and 31 RBIs, while Kyle Schwarber has 59 hits with a team-high 19 home runs and 45 RBIs, but also has a team-high 68 strikeouts as well on the year. Bryce Harper has 8 stolen bases, 13 doubles, 9 home runs, and 34 RBIs. Trea Turner also has 74 hits with a team-high 16 stolen bases. Max Kepler has 12 doubles and Bryson Stott has 6 doubles, 2 triples, 4 homers, and 26 RBIs, while Stott also has 11 stolen bases this season.

Why the Philadelphia Phillies will win

Philadelphia Phillies Player Prop Facts

Pittsburgh Pirates Recap

The Pittsburgh Pirates come into this one looking to bounce back from their 8-2 loss at the hands of the Houston Astros last time out to improve to 23-40 on the year. After this series, the Pirates will square off against the Miami Marlins in a series.

Pirates Split Their Last 8 Games

Bryan Reynolds has 55 hits with 9 doubles, 7 home runs, and 34 RBIs while also leading the Pirates with 70 strikeouts so far this season. Oneil Cruz has posted a team-high 12 home runs and 28 RBIs with 22 stolen bases, while Isiah Kiner-Falefa has 53 hits with 9 stolen bases. Emmanuel Valdez also has a pair of triples this season. Tommy Pham has 4 doubles and Andrew McCutchen has 46 hits with 9 doubles, and KeBryan Hayes has 49 hits with 18 RBIs and 6 stolen bases.

Why the Pittsburgh Pirates will win

Pittsburgh Pirates Player Prop Facts

Total Runs Facts

Philadelphia Phillies vs. Pittsburgh Pirates Prediction

I’m on the Pirates here. Bailey Falter’s pitching really well right now, and this Phillies offense just has not been firing on all cylinders as of late. The Pirates also have the better bullpen over the last week, and I just feel like the value in this game is on the Pirates here. Give me Pittsburgh in this one to draw first blood.

Chris Ruffolo's Pick: Pittsburgh Pirates +114

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