Oakland Athletics vs Houston Astros Prediction 5/27/25 MLB Picks

In this article, we will formulate an Athletics vs Astros prediction for this MLB game on Tuesday, May 27, at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup.

Athletics Betting Preview

The Athletics (23-31, 14-12 Away) were the coldest team in the MLB and went through their worst period of the season after losing 11 consecutive games. During that stretch, the A’s were swept by the Giants and Angels, and were on the brink of getting swept by the Phillies, but managed to win Game 3 and avoid such an outcome. In that 5-4 victory, Logan Davidson led the offense with two RBI, while Gunnar Hoglund pitched for 5.0 innings in a no-decision, allowing three runs on four hits with two strikeouts and three walks. Tyler Ferguson was credited with the win.

This season, the Athletics average 4.28 runs per game (13th in the MLB) on a .256/.321/.419 triple-slash. When it comes to pitching, the Athletics’ staff has a 5.29 ERA (28th) and 1.48 WHIP (28th). Tyler Soderstrom leads the Athletics with a .269 batting average, ten home runs, and 31 RBI this season.

JP Sears will take the mound for the Athletics on Tuesday. The 29-year-old left-hander has a 4-4 record in ten starts this year with a 4.00 ERA and 1.15 WHIP in 54.0 innings.

Houston Astros Betting Preview

The Houston Astros (28-25, 18-10 Home) split the series with the Texas Rangers, lost to the Tampa Bay Rays, and beat the Seattle Mariners. Houston won three of four games in the series against Seattle at home, including the most recent one, when it was 5-3. Christian Walker led the team with three RBI, while Colton Gordon pitched for 5.0 innings in a no-decision, allowing three runs on seven hits with four strikeouts and no walks. Bryan King was credited with the win.

This year, the Astros average 4.04 runs per game (21st in the MLB) on a .254/.323/.386 triple-slash. When it comes to pitching, the Astros’ staff has a 3.42 ERA (8th) and 1.16 WHIP (2nd). Isaac Paredes leads the Astros with a .276 batting average, 11 home runs, and 31 RBI this season.

The projected starting pitcher for the Blue Jays is Hunter Brown, who is 6-3 in ten starts this season, with a 2.04 ERA and 0.91 WHIP in 61.2 innings.

Why the Astros will cover

• The Athletics have lost each of their last six night games against teams that held a winning record.
• The Astros have won seven of their last eight games against the Athletics at Daikin Park following a win.
• The Athletics have failed to cover the run line in each of their last five night games against American League opponents.
• The Astros have covered the run line in nine of their last 11 games against AL West opponents that held a losing record.
• The Athletics have trailed after 5 innings in six of their last seven night games at Daikin Park against American League opponents.
• The Athletics have trailed after 3 innings in three of their last four road games.

Total Runs Facts

• Each of the Athletics’ last five games as underdogs against American League opponents have gone OVER the total runs line.
• Five of the Astros’ last six home games have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 12 of the Athletics’ last 13 games as road underdogs against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last four games as home favorites against American League opponents.

Matchup/League Facts

• The Astros rank T28th in the league for steals this season (24).
• The Astros rank 4th in the league for strikeouts this season (491).
• The Athletics rank 29th in the league for runs allowed this season (308).
• The Athletics rank 28th in the league for ERA this season (5.29).

Athletics vs Astros Prediction

The teams have traded victories in the past couple of years, each recording five in the previous ten H2H encounters. The Athletics were better in four of the last six meetings, but I am backing the Astros to get a win here and cover the run line because of Hunter Brown. Brown did struggle in his last start at Tampa Bay, allowing five runs and three homers, which was shocking, considering he only surrendered two home runs in the season before that game. However, I expect Brown to bounce back here and dominate against the A’s. JP Sears, on the other hand, allowed ten runs and five homers in his last two starts, and the Astros will have a chance to score multiple runs off him early on. Go with the Astros to win and cover.