New York Yankees vs Baltimore Orioles Prediction 4/29/25 MLB Picks

The New York Yankees and the Baltimore Orioles meet Tuesday in MLB action from Camden Yards. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Yankees vs. Baltimore Orioles prediction.

Starting Pitching Matchup

The New York Yankees will send out Carlos Rodon for the start here, and Rodon is 3-3 with a 3.50 ERA and 45 strikeouts this season. In his last five starts against Baltimore, Rodon is 0-2 with a 5.84 ERA and 33 strikeouts. Kyle Gibson will start for Baltimore and was 8-8 with a 4.24 ERA and 151 strikeouts with the Cardinals last season. In his last five starts against the Yankees, Gibson is 2-2 with a 3.60 ERA and 21 strikeouts.

New York Yankees Recap

The New York Yankees will be out to bounce back after starting the series with a 4-3 loss at the hands of Baltimore to fall to 17-12 on the year. After this series, the Yankees will head home for a series against the Tampa Bay Rays.

Yankees Drop Another Series Opener

Aaron Judge leads the Yankees with 45 hits, including 8 home runs, 28 RBIs, 7 doubles, and a .405 batting average, along with 3 stolen bases, while Jazz Chisholm Jr. has 7 home runs, 17 RBIs, and a team-high 6 stolen bases. Anthony Volpe also had 8 doubles with 5 home runs and 18 RBIs, while Jasson Dominguez has added 7 doubles of his own. Paul Goldschmidt has 39 hits with 8 doubles and a .361 batting average, while Chisholm Jr. also has a team-high 39 strikeouts so far this season.

Why the New York Yankees will win

• The Yankees have won each of their last seven games against AL East opponents following a road loss.
• The Orioles have lost 10 of their last 11 games following a win.
• The Yankees have covered the run line in each of their last seven games against AL East opponents following a road loss.
• The Orioles have failed to cover the run line in eight of their last nine games against AL East opponents following a win.

New York Yankees Player Prop Facts

• Anthony Volpe has recorded a Double in four of the Yankees’ last five games as favorites against AL East opponents.
• Carlos Rodon has recorded eight or more strikeouts in each of his last four appearances.
• Carlos Rodon has recorded a win in each of his last five appearances against AL East opponents.
• Paul Goldschmidt has recorded at least one Single in each of the Yankees’ last 14 road games.
• DJ LeMahieu has scored at least one run in each of his last 10 Tuesday appearances against AL East teams that held a losing record.
• Giancarlo Stanton has hit a home run in four of his last five appearances with the Yankees against AL opponents.
• Giancarlo Stanton has recorded at least one RBI in each of his last nine road appearances.
• Giancarlo Stanton has recorded at least one hit in each of his last 10 road appearances.
• Aaron Judge ranks 1st in the league in Hits (45) this season.

Baltimore Orioles Recap

The Baltimore Orioles come into this game looking to add on to their series-opening win over the Yankees last time out to improve to 11-17 on the year. After this series, the Orioles will welcome the Kansas City Royals to town.

Orioles Snap Three-Game Losing Streak

Cedric Mullins has a team-high 26 hits so far this season as well as 5 doubles, 6 home runs, and 20 RBIs with 5 stolen bases and a .292 batting average, while Adley Rutschman has 20 hits with a pair of doubles, 4 homers, and 8 RBIs. Ryan Mountcastle has 17 hits with 4 doubles, and Tyler O’Neill has 14 hits with 3 doubles, a triple, and 2 homers with 10 RBIs. Jordan Westburg added 4 home runs, and Gunnar Henderson has a team-high 26 strikeouts as well this season. Ryan O’Hearn also chipped in 21 hits with 3 doubles and 5 home runs with 11 RBIs, and Heston Kjerstad added 3 homers and 12 RBIs.

Why the Baltimore Orioles will win

• The underdogs have won five of the last six games between the Yankees and Orioles.
• The Yankees have lost nine of their last 14 games as road favorites against AL East opponents.
• The Orioles have covered the run line in each of their last eight Tuesday games as home underdogs against American League opponents.
• The Yankees have failed to cover the run line each of their last five games at Oriole Park at Camden Yards against teams that held a losing record.

Baltimore Orioles Player Prop Facts

• Ryan O’Hearn has hit a home run in four of his last five appearances against AL opponents that held a winning record.
• Gunnar Henderson has recorded a Double in four of the Orioles’ last five night games against opponents that held a winning record.
• Ryan O’Hearn has recorded at least one RBI in four of his last five appearances against AL opponents that held a winning record.
• Ryan O’Hearn has scored a run in each of his last four appearances with the Orioles as underdogs against AL opponents.
• Ryan O’Hearn has recorded at least one hit in each of his last nine appearances with the Orioles as underdogs against AL opponents.
• Ryan Mountcastle has recorded a Single in 10 of the Orioles’ last 11 games against the Yankees.
• Cedric Mullins ranks 5th amongst qualified players for On Base Percentage (.432) this season.

Total Runs Facts

• Each of the Yankees’ last four night games against AL East opponents have gone UNDER the total runs line.
• Each of the Orioles’ last four night games as underdogs have gone UNDER the total runs line.

New York Yankees vs. Baltimore Orioles Prediction

I’m on the Yankees in this one. The Yankees’ comeback attempt on Monday fell short, but they have a better matchup here against Gibson, who is making his season debut and struggled at Camden when he was an Oriole in 2023. Carlos Rodon has been inconsistent, but I think he’s the more trustworthy option here, and the Yankees have the more trustworthy bullpen right now. Give me the Yankees.

Chris Ruffolo's Pick: New York Yankees -155