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New York Yankees vs Arizona Diamondbacks Prediction 9/18/2026 Today’s MLB Picks

Sep 6, 2026; San Diego, California, USA;  New York Yankees pitcher Gerrit Cole (45) pitches against the San Diego Padres during the first inning at Petco Park.  Mandatory Credit: Denis Poroy-Imagn Images

Sep 6, 2026; San Diego, California, USA; New York Yankees pitcher Gerrit Cole (45) pitches against the San Diego Padres during the first inning at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

MATCHUP New York Yankees Arizona Diamondbacks
Team Records 88-64 80-73
Spread -1.5 129 +1.5 -156
Moneyline -131 +109
Total Over 8 (-113) Under 8 (-107)
Where Chase Field, Phoenix, Arizona
When Friday, September 18, 2026
Time 09:40 PM EDT
TV MLB.TV
In this article, we will formulate a Yankees vs Diamondbacks Prediction for this MLB matchup on Friday, September 18th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Arizona Diamondbacks Preview


The Arizona Diamondbacks have a 80-73 record this season and are sitting in the 3rd place of the NL West. They have a 43-35 home record and are coming off a 3-4 home loss against the Marlins. They will face the Rockies and the Padres next.

The Arizona Diamondbacks have a .244 batting average this season, .316 OBP and .397 Slugging percentage. Arizona’s pitching staff has a 4.09 ERA and 1.28 WHIP. Gabriel Moreno is the team’s best hitter with a .307 batting average, adding a team-high 75 RBI. Nolan Arenado adds a team-high 26 home runs.

Eduardo Rodriguez (L) is the projected starting pitcher for the Diamondbacks, and he has a 15-6 record, 2.62 ERA and 1.22 WHIP.

New York Yankees Preview


The New York Yankees have a 88-64 record this season and are sitting in the 2nd place of the AL East. They have a 46-32 away record and are coming off a 4-5 road loss against the Twins. They will face the Rays and the Orioles next.

The New York Yankees have a .235 batting average this season, .312 OBP and .409 Slugging percentage. New York’s pitching staff has a 3.19 ERA and 1.16 WHIP. Cody Bellinger is the team’s best hitter with a .276 batting average. Ben Rice leads the team in RBI with 92, adding a team-high 38 home runs.

Gerrit Cole (R) is the projected starting pitcher for the Yankees, and he has a 8-9 record, 3.67 ERA and 1.13 WHIP.

New York Yankees @ Arizona Diamondbacks Betting Trends: September 18, 2026


Why the Arizona Diamondbacks will win

Why the New York Yankees will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

New York Yankees Player Prop Facts

Matchup/League Facts

Yankees vs Diamondbacks Prediction


Both teams are tied 4-4 in their last 8 meetings and the Yankees have won two of their last three visits in Arizona.

In this Yankees vs Diamondbacks Prediction, the Yankees are coming as -125 road favorites. I like the Yankees on the road in an excellent price. Cole has not been in good form, but Rodriguez has given up 3 runs in each of his last two home starts and the Yankees have been insanely good against lefties in their last 10 games with .328 batting average and 10.1 runs per game. They have also been in better form overall with a 7-2 record in their last 9 games, while the Dbacks are 1-4 in their last 5. Take the Yankees in this one.

Nikos Lagouretos's Pick: New York Yankees ML

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