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Minnesota Twins vs Houston Astros Prediction 6/29/2026 Today’s MLB Picks

Jun 28, 2026; Minneapolis, Minnesota, USA; Minnesota Twins designated hitter Byron Buxton (25) looks on against the Colorado Rockies during the fourth inning at Target Field. Mandatory Credit: Jeffrey Becker-Imagn Images

Jun 28, 2026; Minneapolis, Minnesota, USA; Minnesota Twins designated hitter Byron Buxton (25) looks on against the Colorado Rockies during the fourth inning at Target Field. Mandatory Credit: Jeffrey Becker-Imagn Images

MATCHUP Minnesota Twins Houston Astros
Team Records 40-45 42-44
Spread +1.5 -185 -1.5 152
Moneyline +113 -136
Total Over 9 (-103) Under 9 (-117)
Where Daikin Park, Houston, Texas
When Monday, June 29, 2026
Time 08:10 PM EDT
TV MLB.TV

The Minnesota Twins and the Houston Astros meet Saturday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Minnesota Twins vs. Houston Astros prediction.

Starting Pitching Matchup

The Minnesota Twins will send out Zebby Matthews for the start here and Matthews is 3-5 with a 4.56 ERA and 39 strikeouts this season. Peter Lambert will start for the Astros this season and is 6-4 with a 3.28 ERA and 64 strikeouts this season.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to add on to their 3-2 win over Colorado from Sunday’s matchup to sit at 40-45 this season. After this series, the Twins will head on the road for a series against the Yankees.

Twins Alternate Wins & Losses In 4 Straight

Byron Buxton has 81 hits with 15 doubles, a triple, 25 home runs and 43 RBIs while Josh Bell’s added 72 hits with 16 doubles, 9 home runs and 51 RBIs. Luke Keaschall has 67 hits with 12 doubles, 2 homers and 24 RBIs. Brooks Lee has 14 home runs with 47 RBIs and Victor Caratini has 31 RBIs while Kody Clemens has 61 hits with 16 doubles, 2 triples, 13 home runs and 34 RBIs this season.

Houston Astros Recap

The Houston Astros come into this game looking to add on to their 7-5 win over Detroit last time out to sit at 42-44 this season. After this series, the Astros will take on the Tampa Bay Rays in a series at home.

Astros Win 5 Of Last 6

Yordan Alvarez has 94 hits with 16 doubles, 25 home runs and 56 RBIs while Christian Walker has 76 hits with 16 doubles, 19 home runs and 56 RBIs on the year. Jose Altuve’s chipped in 57 hits with 12 doubles, 8 home runs and 21 RBIs and Isaac Paredes has 73 hits with 16 doubles, 11 home runs and 45 RBIs. Cam Smith also has 61 hits with 12 doubles, 9 home runs and 30 RBIs.

Minnesota Twins @ Houston Astros Betting Trends: June 29, 2026

Why the Houston Astros will win

Why the Minnesota Twins will win

Total Runs Facts

Houston Astros Player Prop Facts

Minnesota Twins Player Prop Facts

Matchup/League Facts

Minnesota Twins vs. Houston Astros Prediction

I’m on the Astros in this one. Both teams have hit right-handed pitching well in June, but it’s the Astros that are just playing the better baseball right now and I think that Lambert is the better starter by a fair margin in this matchup. All in all, I look for the Astros to get the job done in this game.

Chris Ruffolo's Pick: Houston -125

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