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Miami Marlins vs Houston Astros Prediction 7/22/2026 Today’s MLB Picks

Jun 7, 2026; Miami, Florida, USA; Miami Marlins starting pitcher Sandy Alcantara (22) looks on against the Tampa Bay Rays during the first inning at loanDepot Park. Mandatory Credit: Sam Navarro-Imagn Images

Jun 7, 2026; Miami, Florida, USA; Miami Marlins starting pitcher Sandy Alcantara (22) looks on against the Tampa Bay Rays during the first inning at loanDepot Park. Mandatory Credit: Sam Navarro-Imagn Images

MATCHUP Miami Marlins Houston Astros
Team Records 52-50 49-54
Spread -1.5 163 +1.5 -199
Moneyline +100 -120
Total Over 8 (-115) Under 8 (-105)
Where Daikin Park, Houston, Texas
When Wednesday, July 22, 2026
Time 08:10 PM EDT
TV MLB.TV
In this article, we will formulate a Marlins vs Astros Prediction for this MLB matchup on Wednesday, July 22nd in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Houston Astros Preview


The Houston Astros have a 49-54 record this season and are sitting in the 3rd place of the AL West. They have a 25-27 home record and are coming off a 5-3 home win against the Marlins. They will face the White Sox and the Angels next.

The Houston Astros have a .241 batting average this season, .315 OBP and .411 Slugging percentage. Houston’s pitching staff has a 4.75 ERA and 1.40 WHIP. Yordan Alvarez is the team’s best hitter with a .326 batting average, leads the team in RBI with 75, and adds a team-high 33 home runs.

Peter Lambert (R) is the projected starting pitcher for the Houston Astros, and he has an 8-5 record, 3.03 ERA and 1.11 WHIP.

Miami Marlins Preview


The Miami Marlins have a 52-50 record this season and are sitting in the 3rd place of the NL East. They have a 21-30 away record and are coming off a 3-5 road loss against the Astros. They will face the Padres and the Phillies next.

The Miami Marlins have a .252 batting average this season, .328 OBP and .408 Slugging percentage. Miami’s pitching staff has a 4.05 ERA and 1.25 WHIP. Otto Lopez is the team’s best hitter with a .332 batting average. Liam Hicks leads the team in RBI with 60, adding a team-high 14 home runs.

Sandy Alcantara (R) is the projected starting pitcher for the Miami Marlins, and he has a 10-5 record, 3.89 ERA and 1.22 WHIP.

Miami Marlins @ Houston Astros Betting Trends: July 22, 2026


Why the Houston Astros will win


Why the Miami Marlins will win

Total Runs Facts

Houston Astros Player Prop Facts

Miami Marlins Player Prop Facts

Matchup/League Facts

Marlins vs Astros Prediction


The Astros are 9-1 in their last 10 meetings against the Marlins, having won their last five meetings in Houston.

In this Marlins vs Astros Prediction, the Astros are coming as -120 home favorites. The Marlins have been on a free fall lately with eight consecutive wins and they are simply unbackable right now, especially on the road. Peter Lambert has been in excellent form for the Astros with just two earned runs across his last three starts, while Alcantara has been weaker on the road for the Marlins and their offense has fallen off a cliff, as they average just 3.1 runs per game in their last 10 games. Take the Astros to win this one at home.

Nikos Lagouretos's Pick: Houston Astros ML

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