| MATCHUP | Los Angeles Dodgers | San Francisco Giants |
|---|---|---|
| Team Records | 16-6 | 9-13 |
| Where | Oracle Park, San Francisco, California | |
| When | Tuesday, April 21, 2026 | |
| Time | 09:45 PM EDT | |
| TV | MLB.TV | |
The Los Angeles Dodgers and the San Francisco Giants meet Monday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Dodgers vs. San Francisco Giants prediction.
Starting Pitching Matchup
The Los Angeles Dodgers will send out Yoshinobu Yamamoto and Yamamoto is 2-1 with a 2.10 ERA and 21 strikeouts this season. In his last five starts against the Giants, Yamamoto is 0-1 with a 3.03 ERA and 34 strikeouts. San Francisco will send out Landen Roupp for the start here and Roupp is 3-1 with a 2.38 ERA and 24 strikeouts this season. In his career, Roupp is 0-2 with an 8.22 ERA and 8 strikeouts against the Dodgers.
Los Angeles Dodgers Recap
The Los Angeles Dodgers come into this game looking to add on to their 12-3 win over the Colorado Rockies last time out to sit at 16-6 this season. After this series, the Dodgers will head home for a series against the Chicago Cubs.
Dodgers Earn Split Vs. Rockies
Andy Pages has 30 hits with 4 doubles, 5 home runs and 21 RBIs while Teoscar Hernandez has 19 hits with 3 doubles, 4 home runs and 13 RBIs. Shohei Ohtani has 22 hits with 4 doubles, 5 home runs and 11 RBIs and Freddie Freeman has 24 hits with 7 doubles, a triple, 3 home runs and 14 RBIs this season. Will Smith and Mookie Betts each have a pair of home runs as well this season. Max Muncy’s added 23 hits with 8 home runs and Kyle Tucker has 21 hits with 2 doubles, 3 home runs and 13 RBIs this season.
San Francisco Giants Recap
The San Francisco Giants come into this game looking to bounce back from a 3-0 loss at the hands of the Nationals last time out to sit at 9-13 this season. After this series, the Giants will take on the Miami Marlins in a series at home.
Giants Have Three-Game Win Streak Snapped
Luis Arraez has 25 hits with a double, 2 triples and 6 RBIs while Willy Adames has 22 hits with 10 doubles, 3 home runs and 6 RBIs. Matt Chapman has 26 hits with 4 doubles, a triple, a home run and 11 RBIs and Harrison Bader has a home run and 3 RBIs while Jung Hoo Lee has 19 hits with 6 doubles and 8 RBIs. Heliot Ramos has 20 hits with 4 doubles, a home run and 11 RBIs this season. Rafael Devers also has 20 hits with 2 doubles, 2 home runs and 8 RBIs but also has a team-high 28 strikeouts this season.
Los Angeles Dodgers @ San Francisco Giants Betting Trends: April 21, 2026
- Probable Starting Pitcher: Landen Roupp Record this season: 3-1 ERA: 2.38
- Home Record: 0-1
- Last 5 against Dodgers: 0-2
Why the San Francisco Giants will win
- The underdogs have won four of the Giants’ last five games at Oracle Park.
- The Dodgers have lost five of their last six night games at Oracle Park following a win.
- The Giants have covered the run line in each of their last six games as home underdogs following a road loss.
- The Dodgers have failed to cover the run line in five of their last six night games at Oracle Park following a win.
- The Giants have won the first inning in five of their last six night games against NL West opponents that held a winning record.
- The Giants have led after 5 innings in five of their last six games against NL West opponents.
- The Giants have led after 3 innings in each of their last five night games against NL West opponents.
- Probable Starting Pitcher: Yoshinobu Yamamoto Record this season: 2-1 ERA: 2.10
- Road Record: 1-0
- Last 5 against Giants: 0-1
Why the Los Angeles Dodgers will win
- The Dodgers have won 14 of their last 15 night games against teams that held a losing record.
- The Giants have lost eight of their last nine night games against teams that held a winning record.
- The Giants have failed to cover the run line in six of their last seven home games against NL West opponents that held a winning record.
- The Dodgers have covered the run line in five of their last six games against National League opponents following a road win.
- The Dodgers have led after 5 innings in eight of their last nine road games against NL West opponents.
- The Dodgers have led after 3 innings in seven of their last eight road games against NL West opponents.
Total Runs Facts
- Each of the Giants’ last four games as underdogs against National League opponents have gone UNDER the total runs line.
- Three of the Dodgers’ last four games after playing the previous day have gone OVER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Giants’ last eight home games against NL West opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Dodgers’ last four night games against NL West opponents.
San Francisco Giants Player Prop Facts
- Heliot Ramos has hit a home run in two of the Giants’ last three games.
- Luis Arraez has recorded at least one hit in each of his last 10 appearances in night games against teams that held a winning record.
- Landen Roupp ranks T5th in the league for Wins (3) this season.
Los Angeles Dodgers Player Prop Facts
- Mookie Betts has hit a home run in four of his last six appearances in night games against teams that held a losing record.
- Freddie Freeman has recorded at least one hit in each of his last 15 road appearances against NL opponents.
- Andy Pages ranks T1st in the league in Hits (30) this season.
Matchup/League Facts
- The Giants rank 30th in the league for steals this season (5).
- The Giants rank 30th in the league for walks this season (43).
- The Dodgers rank 1st in the league for runs scored this season (133).
- The Dodgers rank 1st in the league for hits this season (222).
Los Angeles Dodgers vs. San Francisco Giants Prediction
I’m on the under in this one. I think that Yamamoto can have a solid start against a Giants team that continues to be wildly ineffective offensively, but I also think that Landen Roupp can have a strong start against a Dodger lineup that is imposing, but is coming off of a series at Coors Field with no day off in between to reacclimate themselves from the difference in altitude. I think that the under is in play here so give me the under in a low-scoring battle.