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Los Angeles Dodgers vs Houston Astros Prediction 5/6/2026 Today’s MLB Picks

May 5, 2026; Houston, Texas, USA; Houston Astros shortstop Braden Shewmake (28) motions as he rounds the bases on a solo home run in the third inning against the Los Angeles Dodgers at Daikin Park. Mandatory Credit: Maria Lysaker-Imagn Images

May 5, 2026; Houston, Texas, USA; Houston Astros shortstop Braden Shewmake (28) motions as he rounds the bases on a solo home run in the third inning against the Los Angeles Dodgers at Daikin Park. Mandatory Credit: Maria Lysaker-Imagn Images

MATCHUP Los Angeles Dodgers Houston Astros
Team Records 22-14 15-22
Spread -1.5 -126 +1.5 104
Moneyline -219 +179
Total Over 9 (100) Under 9 (-121)
Where Daikin Park, Houston, Texas
When Wednesday, May 6, 2026
Time 02:10 PM EDT
TV MLB.TV
The Los Angeles Dodgers and Houston Astros meet Wednesday in MLB action at Daikin Park. Here’s a Los Angeles Dodgers vs. Houston Astros Prediction. This article will include a Los Angeles Dodgers vs. Houston Astros Pick.

Los Angeles Dodgers Betting Preview


The Los Angeles Dodgers are 22-14 on the year and play the Giants and Braves next. The Los Angeles Dodgers are batting. 271 on the season and have a .350 OBP, and a .438 slugging percentage. The Los Angeles Dodgers pitching staff has a 3.19 ERA and a 1.11 WHIP. Andy Pages leads the Los Angeles Dodgers with 43 hits and 27 RBI, while Freddie Freeman and Max Muncy have combined for 71 hits and 31 RBI.

Tyler Glasnow gets the ball for the Los Angeles Dodgers, and he is 3-0 with a 2.56 ERA and 47 strikeouts this season. This will be Glasnow’s second career game against the Houston Astros.

Houston Astros Betting Preview


The Houston Astros are 15-22 on the year and play the Mariners and Reds next. The Houston Astros are batting. 264 on the season, have a .342 OBP, and have a .433 slugging percentage. The Houston Astros pitching staff has a 5.65 ERA and a 1.62 WHIP. Yordan Alvarez leads the Houston Astros with 45 hits and 27 RBI while Carlos Correa and Christian Walker have combined for 75 hits and 43 RBI.

Lance McCullers Jr. gets the ball for the Houston Astros, and he is 2-2 with a 6.32 ERA and 33 strikeouts this season. McCullers is 2-0 with a 1.14 ERA and 26 strikeouts in his career against the Los Angeles Dodgers.

Why the Houston Astros will win

Why the Los Angeles Dodgers will win

Total Runs Facts

Houston Astros Player Prop Facts

Los Angeles Dodgers Player Prop Facts

Matchup/League Facts

Los Angeles Dodgers vs Houston Astros Prediction


The Dodgers are burning a hole in the pocket with all of these inflated lines and losses. I wouldn’t blame you for looking the other way. However, Glasnow has been dealing up to this point and the Astros’ pitching staff remains a mess. McCullers has played a role in the struggles, as he’s coming off an April where he had a 7.77 ERA in 24.1 innings. Massive pitching edge for the Dodgers and at some point they’re going to run into a victory. I’ll take the Dodgers and the RL for max betting value.

Randy Chambers's Pick: Los Angeles Dodgers -1.5

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