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Los Angeles Angels vs Chicago White Sox Prediction 3/29/25 MLB Picks

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Chicago White Sox (1-0) vs Los Angeles Angels (0-1)

Game Info: Saturday, March 29, 2025 at 2:10 pm (Rate Field)

The Line: Betting Odds: Chicago White Sox +140 / Los Angeles Angels -166 — Over/Under: 8

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In this article, we will formulate a Los Angeles Angels vs Chicago White Sox prediction for this MLB game on Saturday, March 29th, at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Los Angeles Angels Betting Preview

The Los Angeles Angels are 0-1 this year after they lost to the Chicago White Sox by a score of 8-1 in their last game. Los Angeles allowed the first eight runs in the game, but they did score in the ninth inning on a home run from O’Hoppe to avoid the shutout. The Angels only trailed 3-0 late in the game, but they allowed five runs in the eighth to blow the game open, and they only recorded five hits in the loss. O’Hoppe went 2-4 in the game with one home run and one RBI, while Adell, Ward, and Schanuel added one hit each. Kikuchi started the game on the mound for LA and went 6.0 innings, allowing five hits and three earned runs. Johnson came on in relief in the seventh inning, and he allowed five earned runs over 1.2 innings of work. The Angels will meet the Cardinals after this series.

Last season, the Los Angeles pitching staff had a 4.56 ERA with a 1.35 WHIP and a .246 opponent batting average, while the offense scored 635 runs with a .229 batting average and a .301 on-base percentage. The Angels were near the bottom of the MLB in team ERA and runs scored, and they had a pretty rough season. LA was led by Taylor Ward, who hit .246 with 25 home runs and 75 RBIs in 2024. The projected starting pitcher for Los Angeles is Jose Soriano, who went 6-7 with a 3.42 ERA and a 1.20 WHIP over 113.0 innings pitched last season. 

Chicago White Sox Betting Preview

The Chicago White Sox are 1-0 this season after they defeated the Angels in game one of the series by a score of 8-1. Chicago took a 3-0 lead in the second inning on a home run from Slater and a double from Vargas, and they never looked back from there. The White Sox were able to tack on five runs in the eighth but did lose the shutout in the ninth. Benintendi went 1-4 with three RBIs, while Vargas and Sosa added two RBIs in the game. Burke started on the mound for Chicago, and he allowed just three hits over 6.0 innings of work for the win. The Cubs will face the Twins and Tigers following this series.

Last season, the Chicago pitching staff had a 4.67 ERA with a 1.44 WHIP and a .255 opponent batting average, while the offense scored 507 runs with a .221 batting average and a .278 on-base percentage. Chicago was dead last in runs scored last season, and they were 28th in team ERA. The White Sox were led by Andrew Benintendi, who hit .229 with 20 home runs and 64 RBIs last year. The projected starting pitcher for Chicago is Jonathan Cannon, who was 5-10 with a 4.49 ERA and a 1.33 WHIP over 124.1 innings pitched last year. 

Why the White Sox will beat the Angels 

Total Runs Facts

Chicago White Sox Player Prop Facts

Los Angeles Angels Player Prop Facts

Los Angeles Angels vs Chicago White Sox Prediction 

The Angels started the season with a very disappointing loss in game one of this series to a White Sox team that was historically bad last year, and they will look to bounce back here. Los Angeles should have a decent lineup this season, but they managed just one run in their first game and will face a decent pitcher here. Chicago should have plenty of positive momentum coming into this game, and I think they have great value with the plus money. Take the White Sox to win another one!

David Racey's Pick: White Sox ML

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