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Houston Astros vs Oakland Athletics Prediction 4/4/2026 Today’s MLB Picks

Apr 3, 2026; West Sacramento, California, USA; Houston Astros third baseman Nick Allen (20) beats the throw to Athletics first baseman Nick Kurtz (16) for an infield hit during the seventh inning at Sutter Health Park. Mandatory Credit: D. Ross Cameron-Imagn Images

Apr 3, 2026; West Sacramento, California, USA; Houston Astros third baseman Nick Allen (20) beats the throw to Athletics first baseman Nick Kurtz (16) for an infield hit during the seventh inning at Sutter Health Park. Mandatory Credit: D. Ross Cameron-Imagn Images

MATCHUP Houston Astros Oakland Athletics
Team Records 5-3 2-5
Spread -1.5 135 +1.5 -163
Moneyline -115 -105
Total Over 10 (-102) Under 10 (-118)
Where Sutter Health Park, Sacramento, California
When Saturday, April 4, 2026
Time 04:05 PM EDT
TV MLB.TV

In this article, we will formulate an Astros vs Athletics Prediction for this MLB matchup on Saturday, April 4th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Athletics Preview

The Athletics have a 2-5 record this season and are sitting in the last place of the AL West. They have a 1-0 home record and are coming off an 11-4 home win over the Astros. Their previous three games were a 1-5 road loss, a 5-2 road win and a 0-4 road loss to the Braves.

The Athletics have a .206 batting average this season, .266 OBP and .348 Slugging percentage. Oakland’s pitching staff has a 4.28 ERA and 1.48 WHIP. Shea Langeliers is the team’s best hitter with a .333 batting average, also leading the team in RBI with 8 and adding a team-high 5 home runs.

Luis Morales (R) is the projected starting pitcher for the Athletics, and he has a 0-1 record, 10.38 ERA and 1.62 WHIP.

Houston Astros Preview

The Houston Astros have a 5-3 record this season and are sitting in the first place of the AL West. They have a 0-1 road record and are coming off a 4-11 road loss to the Athletics. Their previous three games were a 6-4, a 9-2 and an 8-1 home win over the Red Sox.

The Astros have a .259 batting average this season, .357 OBP and .440 Slugging percentage. Houston’s pitching staff has a 5.45 ERA and 1.46 WHIP. Yordan Alvarez is the team’s best hitter with a .400 batting average, also adding a team-high three home runs. Carlos Correa leads the team in RBI with 7.

Tatsuya Imai (R) is the projected starting pitcher for the Astros, and he has a 0-0 record, 13.50 ERA and 2.63 WHIP.

Houston Astros @ Athletics Betting Trends: April 4, 2026

Why the Athletics will win

Why the Houston Astros will win

Total Runs Facts

Athletics Player Prop Facts

Houston Astros Player Prop Facts

Matchup/League Facts

Astros vs Athletics Prediction

The Athletics are 8-1 in their last 9 meetings against the Astros and are 4-1 in their last 5 meetings at home.

In this Astros vs Athletics Prediction, the Astros are coming as -115 road favorites. The Astros saw their five-game winning streak getting snapped yesterday and today they are going with Tatsuya Imai on the mound who got lit up in just 2.2 innings pitched in his first start. Morales is also coming of a terrible first start to the season where he gave up 5 runs in 4.1 innings pitched and both teams are a perfect 7-0 to the over in their last 7 games combined, as they average 10.5 runs per game combined. This is going to be a slugfest so take the over 10 runs.

Nikos Lagouretos's Pick: Over 10

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