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Colorado Rockies vs Cincinnati Reds Prediction 4/29/2026 Today’s MLB Picks

Cincinnati Reds shortstop Elly de la Cruz (44) takes off for first base on a two-run home run in the eighth inning of the MLB National League game between the Cincinnati Reds and the Colorado Rockies at Great American Ball Park in downtown Cincinnati on Tuesday, April 28, 2026. The Reds won the opening game of the series, 7-2.

Cincinnati Reds shortstop Elly de la Cruz (44) takes off for first base on a two-run home run in the eighth inning of the MLB National League game between the Cincinnati Reds and the Colorado Rockies at Great American Ball Park in downtown Cincinnati on Tuesday, April 28, 2026. The Reds won the opening game of the series, 7-2.

MATCHUP Colorado Rockies Cincinnati Reds
Team Records 13-17 19-10
Spread +1.5 -163 -1.5 135
Moneyline +129 -156
Total Over 9.5 (100) Under 9.5 (-120)
Where Great American Ball Park, Cincinnati, Ohio
When Wednesday, April 29, 2026
Time 06:40 PM EDT
TV MLB.TV

The Colorado Rockies and Cincinnati Reds meet Wednesday in MLB action at Great American Ball Park. Here’s a Colorado Rockies vs. Cincinnati Reds Prediction. This article will include a Colorado Rockies vs. Cincinnati Reds Pick.

Colorado Rockies Betting Preview

The Colorado Rockies are 13-17 on the year and play the Mets and Braves next. The Colorado Rockies are batting .249 on the season and have a .316 OBP, and a .393 slugging percentage. The Colorado Rockies pitching staff has a 4.19 ERA and a 1.37 WHIP. Troy Johnston leads the Colorado Rockies with 29 hits and 16 RBI while TJ Rumfield and Mickey Moniak have combined for 53 hits and 31 RBI.

Tomoyuki Sugano gets the ball for the Colorado Rockies, and he is 2-1 with a 3.42 ERA and 19 strikeouts this season. This will be Sugano’s first career game against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 19-10 on the year and play the Pirates and Cubs next. The Cincinnati Reds are batting. 218 on the season, have a .309 OBP, and have a .384 slugging percentage. The Cincinnati Reds pitching staff has a 3.71 ERA and a 1.40 WHIP. Elly De La Cruz leads the Cincinnati Reds with 34 hits and 24 RBI, while Sal Stewart and Matt McLain have combined for 53 hits and 38 RBI.

Brandon Williamson gets the ball for the Cincinnati Reds, and he is 2-2 with a 5.40 ERA and 15 strikeouts this season. Williamson is 0-0 with a 3.38 ERA and 11 strikeouts in his career against the Colorado Rockies.

Why the Cincinnati Reds will win

Why the Colorado Rockies will win

Total Runs Facts

Cincinnati Reds Player Prop Facts

Colorado Rockies Player Prop Facts

Matchup/League Facts

Colorado Rockies vs Cincinnati Reds Prediction

I’m not excited to get behind Williamson and his 5.40 ERA and 1.52 WHIP, and he’s walked 16 in 25 innings. It’s not great. However, the Reds are playing better baseball overall, while the Rockies remain a below-average team that’s going to lose long term. It’s one of those spots where you just back the better team and believe things will work out. Not a great pitching matchup, but I’m rolling with the Reds at home with the cheap price.

Randy Chambers's Pick: Cincinnati Reds

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