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Colorado Rockies vs Chicago Cubs Prediction 5/26/25 MLB Picks

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Chicago Cubs (32-21) vs Colorado Rockies (9-44)

Game Info: Monday, May 26, 2025 at 2:20 pm (Wrigley Field)

The Line: Betting Odds: Chicago Cubs -355 / Colorado Rockies +280 — Over/Under: 8

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The Colorado Rockies and the Chicago Cubs meet Monday in MLB action from Wrigley Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Colorado Rockies vs. Chicago Cubs prediction.

Starting Pitching Matchup

The Colorado Rockies will send out Carson Palmquist for the start here and is 0-2 with an 11.88 ERA and 2 strikeouts this season. This will be Palmquist’s first career start against the Cubs. The Chicago Cubs will trot out Jameson Taillon here, and Taillon is 3-3 with a 4.13 ERA and 44 strikeouts this season. In his last five starts against the Rockies, Taillon is 3-1 with a 2.03 ERA and 26 strikeouts.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from their 5-4 loss at the hands of the New York Yankees last time out to slip to 9-44 on the year. After this series, the Rockies will head on the road for another series against the New York Mets.

Rockies Still Looking For Win #10

Hunter Goodman leads the Rockies with 53 hits, including 11 doubles, 7 home runs, and 31 RBIs, while Michael Toglia has 35 hits with 9 doubles, 6 home runs, and 20 RBIs but also has a team-high 74 strikeouts. Kyle Farmer has a team-high 13 doubles while Jordan Beck has 8 home runs, 16 RBIs, 4 triples, and 6 stolen bases. Brenton Doyle has 36 hits with 7 doubles, 4 home runs, 19 RBIs, and 6 stolen bases. Mickey Moniak has 30 hits with 4 doubles, 4 triples, and 4 home runs with 14 RBIs.

Why the Colorado Rockies will win

Colorado Rockies Player Prop Facts

Chicago Cubs Recap

The Chicago Cubs come into this game looking to keep the ball rolling after an 11-8 win over the Cincinnati Reds in Sunday’s series finale to bring their record to 32-21 on the year. After this series, the Cubs will welcome the Reds to town for a series rematch.

Cubs Win 7 Of Their Last 9

Ian Happ has 46 hits with 9 doubles, 3 home runs, and 21 RBIs. Kyle Tucker has 58 hits, including 9 doubles, 4 triples, 12 home runs, and 37 RBIs, while Seiya Suzuki also has 54 hits with 14 doubles and 14 home runs and 49 RBIs of his own. Miguel Amaya added 9 doubles and 25 RBIs, and Pete Crow-Armstrong also has contributed 60 hits, 13 doubles, 3 triples, 14 home runs, and 48 RBIs as well this season. Dansby Swanson has added 11 home runs and 29 RBIs, while Suzuki has the unfortunate distinction of leading the Cubs with 59 strikeouts so far this season. Crow-Armstrong also has a team-high 14 stolen bases, while Nico Hoerner has 11 stolen bases this season. Tucker’s also added 14 stolen bases, while Michael Busch has also chipped in 7 home runs and 28 RBIs this season.

Why the Chicago Cubs will win

Chicago Cubs Player Prop Facts

Total Runs Facts

Colorado Rockies vs. Chicago Cubs Prediction

I’m on the Cubs here. I just have a hard enough time getting behind the Rockies at the best of times and now coming on the road a day after playing a series at home, there’s not really much of an adjustment period to get acclimated and that’s why the Rockies tend to struggle on the road, especially in the first game off of a homestand. The Cubs are playing really well right now, and I’m not trying to get in front of them when the Rockies are the alternative and when Palmquist just doesn’t look ready for the major leagues. I’ll roll with the Cubs big in this one.

Chris Ruffolo's Pick: Chicago Cubs -1.5

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