Colorado Rockies vs Arizona Diamondbacks Prediction 5/16/25 MLB Picks

The Colorado Rockies are visiting the Arizona Diamondbacks on Friday, May 16th at the Chase Field in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Colorado Rockies vs Arizona Diamondbacks Prediction. We will examine:

The Arizona Diamondbacks’ recent form and player performance

The Colorado Rockies’ recent form and player performance

Recent betting trends and streaks involving the Arizona Diamondbacks

Recent betting trends and streaks involving the Colorado Rockies

Recent betting trends in games played between the Colorado Rockies and the Arizona Diamondbacks

A summary that ties it all together and produces a favorable betting outcome for the Colorado Rockies vs Arizona Diamondbacks game

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 23-21 record this season and are sitting in 4th place in the NL West. The Diamondbacks have an 11-12 home record and are 19-21 in over/under. They are coming off an 8-7 road victory over the San Francisco Giants and have been alternating wins and losses for the past two weeks. Under is 7-3 in their last 10 games, and are playing the Dodgers and the Cardinals next.

The Diamondbacks have a .252 batting average this season, a .335 OBP, and a .444 slugging percentage. Arizona’s pitching staff has a 4.71 ERA and 1.35 WHIP. Corbin Carroll leads the Diamondbacks with 52 hits and a team-high 14 home runs. Josh Naylor is the team’s best hitter with a .299 batting average, while Eugenio Suarez leads the team in RBI, with 31.

Corbin Burnes (R) will take the mound for the Diamondbacks, and he has a 2-1 record, 2.95 ERA, and 1.31 WHIP. He has been better at home, with a 1.96 ERA across three starts, and he has been on fire lately, having just two earned runs in 18.1 innings of work in his last three starts.     

Colorado Rockies Preview

The Colorado Rockies have a 7-36 record this season and are sitting in last place in the NL West. The Rockies have a 2-20 road record and are 18-24 in over/under. They are coming off a 3-8 road defeat by the Texas Rangers, and are 1-11 in their last 12 games. Over is 9-2 in their last 11 games, and they are playing the Phillies and the Yankees next.

The Rockies have a .217 batting average this season, a .284 OBP, and a .354 Slugging percentage. Colorado’s pitching staff has a 5.73 ERA and 1.59 WHIP.  Hunter Goodman leads the Rockies with 44 hits, adding a team-high 25 RBI, and he is the team’s best hitter with a .291 batting average. Ryan McMahon adds a team-high 6 home runs.

Carson Palmquist (R) will take the mound for the Rockies, and he will make his MLB debut tonight. The Rockies drafted Palmquist out of the University of Miami in the third round of the 2022 draft, with the No. 88 overall choice. In seven starts for the Isotopes this season, Palmquist has a 3.72 ERA. He has pitched in 35.1 innings with 45 strikeouts, 18 walks, and a 1.13 WHIP.

Why the Arizona Diamondbacks will win

• The Rockies have lost each of their last 18 games following a road loss.
• The Diamondbacks have won seven of their last eight home games against the Rockies.
• The Rockies have failed to cover the run line in each of their last seven night games following a loss.
• The favorites have covered the run line in 10 of the Rockies’ last 12 games.
• The Rockies have trailed after 3 innings in nine of their last 10 road games against opponents that held a winning record.
• The Rockies have trailed after 5 innings in each of their last nine Friday night games as road underdogs.
• The Rockies have lost the first inning in four of their last five night games against NL West opponents.

Why the Colorado Rockies will win

• The Diamondbacks have lost nine of their last 10 games as home favorites against National League opponents following a win.
• The Rockies have won three of their last four night games against the Diamondbacks following a loss.
• The Diamondbacks have failed to cover the run line in 12 of their last 13 home games against National League opponents following a win.
• The Rockies have covered the run line in each of their last four night games against the Diamondbacks following a loss.
• The Diamondbacks have trailed after 3 innings in each of their last three night games against NL West opponents that held a losing record.
• The Diamondbacks have trailed after 5 innings in five of their last six home games against NL West opponents that held a losing record.

Total Runs Facts

• Each of the Rockies’ last five games against NL West opponents have gone OVER the total runs line.
• Six of the Diamondbacks’ last seven home games have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rockies’ last four games as underdogs against NL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the last 12 night games between the Rockies and Diamondbacks at Chase Field.

Matchup/League Facts

• The Diamondbacks rank 1st in the league for doubles this season (88).
• The Diamondbacks rank T1st in the league for walks this season (173).
• The Rockies rank T1st in the league for triples this season (11).
• The Rockies rank 30th in the league for strikeouts against this season (418).

Colorado Rockies vs Arizona Diamondbacks Prediction

In their 13 meetings last season, the Dbacks led the Rockies with 9-4 wins, and were 6-1 in their 7 meetings in Arizona, and over was 5-2 in those 7 meetings.

In this Colorado Rockies vs Arizona Diamondbacks Prediction, the Diamondbacks are coming as huge -400 home favorites. The Diamondbacks are rightfully favored, as they have been the superior team this season, mostly because the Rockies are by far the worst team in the MLB so far. But the Dbacks manage to have a worse bullpen than the Rockies, and I don’t think the Rockies will touch Burnes, so I like the Dbacks to have a dominating lead in the first 5 innings of the game. In order not to lay a huge price, I will take the Dbacks by -1.5 runs in the F5 innings.