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Colorado Rockies vs Arizona Diamondbacks Prediction 5/23/2026 Today’s MLB Picks

May 22, 2026; Phoenix, Arizona, USA; Colorado Rockies catcher Hunter Goodman (15) and pitcher Antonio Senzatela (49) celebrate after defeating the Arizona Diamondbacks in the fifth inning at Chase Field. Mandatory Credit: Rick Scuteri-Imagn Images

May 22, 2026; Phoenix, Arizona, USA; Colorado Rockies catcher Hunter Goodman (15) and pitcher Antonio Senzatela (49) celebrate after defeating the Arizona Diamondbacks in the fifth inning at Chase Field. Mandatory Credit: Rick Scuteri-Imagn Images

MATCHUP Colorado Rockies Arizona Diamondbacks
Team Records 20-32 26-24
Spread +1.5 -133 -1.5 110
Moneyline +152 -185
Total Over 9 (-120) Under 9 (100)
Where Chase Field, Phoenix, Arizona
When Saturday, May 23, 2026
Time 10:10 PM EDT
TV MLB.TV

The Colorado Rockies and Arizona Diamondbacks meet Saturday in MLB action at Chase Field. Here’s a Colorado Rockies vs. Arizona Diamondbacks Prediction. This article will include a Colorado Rockies vs. Arizona Diamondbacks Pick.

Colorado Rockies Betting Preview

The Colorado Rockies are 20-32 on the year and play the Giants and Dodgers next. The Colorado Rockies are batting .244 on the season and have a .311 OBP, and a .381 slugging percentage. The Colorado Rockies pitching staff has a 4.88 ERA and a 1.46 WHIP. TJ Rumfield leads the Colorado Rockies with 51 hits and 26 RBI while Troy Johnston and Hunter Goodman have combined for 91 hits and 41 RBI.

Michael Lorenzen gets the ball for the Colorado Rockies, and he is 2-6 with a 7.03 ERA and 36 strikeouts this season. Lorenzen is 3-2 with a 3.77 ERA and 25 strikeouts in his career against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 26-24 on the year and play the Mariners and Giants next. The Arizona Diamondbacks are batting. 244 on the season, have a .311 OBP, and have a .397 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.14 ERA and a 1.26 WHIP. Ildemaro Vargas leads the Arizona Diamondbacks with 55 hits and 32 RBI while Ketel Marte and Corbin Carroll have combined for 93 hits and 48 RBI.

Zac Gallen gets the ball for the Arizona Diamondbacks, and he is 2-4 with a 4.78 ERA and 34 strikeouts this season. Gallen is 9-1 with a 3.41 ERA and 121 strikeouts in his career against the Colorado Rockies.

Why the Arizona Diamondbacks will win

Why the Colorado Rockies will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

Colorado Rockies Player Prop Facts

Matchup/League Facts

Colorado Rockies vs Arizona Diamondbacks Prediction

The Rockies have had issues stringing wins together and Lorenzen isn’t a pitcher I’m excited to get behind with his 7.03 ERA and 1.91 WHIP through 48.2 innings. Gallen is better than what he’s shown this season and he’s owned the Rockies throughout his career. Gallen has also been at his best at home this season with a 2.70 ERA and a .238 allowed batting average in 26.2 innings. All of Gallen’s issues this season have come on the road. Give me the Diamondbacks.

Randy Chambers's Pick: Arizona Diamondbacks

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