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Colorado Rockies vs Arizona Diamondbacks Prediction 5/22/2026 Today’s MLB Picks

May 21, 2026; Phoenix, Arizona, USA; Arizona Diamondbacks right fielder Corbin Carroll (7) is doused with gum by Arizona Diamondbacks left fielder Lourdes Gurriel Jr. (12) after hitting a walk off single against the Colorado Rockies during the ninth inning at Chase Field. Mandatory Credit: Joe Camporeale-Imagn Images

May 21, 2026; Phoenix, Arizona, USA; Arizona Diamondbacks right fielder Corbin Carroll (7) is doused with gum by Arizona Diamondbacks left fielder Lourdes Gurriel Jr. (12) after hitting a walk off single against the Colorado Rockies during the ninth inning at Chase Field. Mandatory Credit: Joe Camporeale-Imagn Images

MATCHUP Colorado Rockies Arizona Diamondbacks
Team Records 19-32 26-23
Spread +1.5 -120 -1.5 -101
Moneyline +178 -218
Total Over 9 (100) Under 9 (-121)
Where Chase Field, Phoenix, Arizona
When Friday, May 22, 2026
Time 09:40 PM EDT
TV MLB.TV

The Colorado Rockies and Arizona Diamondbacks meet Friday in MLB action at Chase Field. Here’s a Colorado Rockies vs Arizona Diamondbacks Prediction. This article will include a Colorado Rockies vs Arizona Diamondbacks Pick.

Colorado Rockies Betting Preview

The Colorado Rockies are 19-32 on the year and play the Giants and Dodgers next. The Colorado Rockies are batting .243 on the season and have a .311 OBP, and a .383 slugging percentage. The Colorado Rockies pitching staff has a 4.94 ERA and a 1.47 WHIP. TJ Rumfield leads the Colorado Rockies with 50 hits and 25 RBI while Troy Johnston and Mickey Moniak have combined for 90 hits and 50 RBI.

Tomoyuki Sugano gets the ball for the Colorado Rockies, and he is 4-3 with a 4.02 ERA and 25 strikeouts this season. This will be Sugano’s second career game against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 26-23 on the year and play the Mariners and Giants next. The Arizona Diamondbacks are batting. 244 on the season, have a .311 OBP, and have a .399 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.17 ERA and a 1.26 WHIP. Ildemaro Vargas leads the Arizona Diamondbacks with 55 hits and 32 RBI while Ketel Marte and Corbin Carroll have combined for 90 hits and 48 RBI.

Michael Soroka gets the ball for the Arizona Diamondbacks, and he is 6-2 with a 3.49 ERA and 55 strikeouts this season. Soroka is 1-2 with a 2.87 ERA and 23 strikeouts in his career against the Colorado Rockies.

Why the Arizona Diamondbacks will win

Why the Colorado Rockies will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

Colorado Rockies Player Prop Facts

Matchup/League Facts

Colorado Rockies vs Arizona Diamondbacks Prediction

The Rockies are looking more and more like the Rockies we expected to see out of the gate, and I’m going to continue fading them. The Diamondbacks have played their best ball over the last week and Soroka has been strong with a 3.49 ERA and 1.33 WHIP through 49 innings. Sugano has allowed 17 hits and 11 runs in his last 15.1 innings. Give me the Diamondbacks for another victory.

Randy Chambers's Pick: Arizona Diamondbacks

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