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Cleveland Guardians vs Toronto Blue Jays Prediction 5/4/25 MLB Picks

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Toronto Blue Jays (16-17) vs Cleveland Guardians (19-14)

Game Info: Sunday, May 4, 2025 at 1:37 pm (Rogers Centre)

The Line: Betting Odds: Toronto Blue Jays -115 / Cleveland Guardians -105 — Over/Under: 8

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The Cleveland Guardians and the Toronto Blue Jays meet Saturday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cleveland Guardians vs. Toronto Blue Jays prediction.

Starting Pitching Matchup

The Cleveland Guardians will send out Tanner Bibee for the start here, and Bibee is 2-2 with a 4.36 ERA and 25 strikeouts this season. In his career, Bibee is 2-0 with a 1.38 ERA and 11 strikeouts against Toronto. Bowden Francis will start this one for the Blue Jays and is 2-4 with a 5.28 ERA and 23 strikeouts this season. This will be Francis’s first career start against the Guardians.

Cleveland Guardians Recap

The Cleveland Guardians will look to keep the ball rolling after picking up a 5-3 win over the Blue Jays in Saturday’s matchup to improve to 19-14 on the year. After this series, the Guardians will head on the road for a series against the Nationals.

Guardians Win 4 Of Their Last 5

Steven Kwan leads the Guardians with 41 hits as part of a .323 batting average and 4 home runs, 6 doubles, and 15 RBIs. Kyle Manzardo has 21 hits with 3 doubles, a triple, 8 home runs, and a team-high 20 RBIs as well this year. Gabriel Arias has a team-high 6 doubles but also has a team-high 31 strikeouts, and Manzardo has 29 strikeouts so far this season. Arias has also added 4 home runs and 11 RBIs, and Jose Ramirez has chipped in 5 home runs and 15 RBIs.

Why the Cleveland Guardians will win

Cleveland Guardians Player Prop Facts

Toronto Blue Jays Recap

The Toronto Blue Jays will try to rebound from their loss at the hands of the Guardians in Saturday’s clash to drop to 16-17 on the year. After this series, the Blue Jays will head on the road for a series against the Los Angeles Angels.

Blue Jays Have Three-Game Win Streak Snapped

George Springer has 27 hits and Bo Bichette has 39 hits, with Springer adding 3 home runs, a triple, 7 doubles, and 13 RBIs while Bichette has 10 doubles and 13 RBIs. Andres Gimenez has added 20 hits with 4 doubles and 3 home runs and 8 RBIs this season, along with 8 stolen bases, while Anthony Santander has a team-high 31 strikeouts so far this season. Vladimir Guerrero Jr. also has 4 homers, 6 doubles, and 17 RBIs, while Springer also has a .314 batting average up to this point in the year.

Why the Toronto Blue Jays will win

Toronto Blue Jays Player Prop Facts

Total Runs Facts

Cleveland Guardians vs. Toronto Blue Jays Prediction

I’m on the over in this game. Bibee has allowed 13 runs in his last two road starts, and I think the Blue Jays’ bats can get to him, and this Guardians bullpen has not been as effective as we’re used to them being in years past. On the other side, Francis has had a serious issue with home runs this season and giving them up, and I think the Guardians could go yard a few times here. Give me the over in this one.

Chris Ruffolo's Pick: Over 8

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