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Cleveland Guardians vs Tampa Bay Rays Prediction 10/12/2026 Today’s MLB Picks

Sep 22, 2026; Bronx, New York, USA; Tampa Bay Rays starting pitcher Drew Rasmussen (57) follows through on a pitch against the New York Yankees during the first inning at Yankee Stadium. Mandatory Credit: Brad Penner-Imagn Images

Sep 22, 2026; Bronx, New York, USA; Tampa Bay Rays starting pitcher Drew Rasmussen (57) follows through on a pitch against the New York Yankees during the first inning at Yankee Stadium. Mandatory Credit: Brad Penner-Imagn Images

MATCHUP Cleveland Guardians Tampa Bay Rays
Team Records 85-77 98-64
Spread +1.5 -157 -1.5 130
Moneyline +142 -172
Total Over 6.5 (-122) Under 6.5 (101)
Where Tropicana Field, St. Petersburg, Florida
When Monday, October 12, 2026
Time 08:00 PM EDT
TV TBS
In this article, we will formulate a Guardians vs Rays Prediction for this MLB matchup on Monday, October 12th in Game 1 of this ALCS matchup. Let’s take a look at the prediction for this MLB matchup.

Tampa Bay Rays Preview


The Tampa Bay Rays finished the regular season with a 98-64 record and were placed 1st in the AL East. They have a 55-26 home record and are coming off a 4-3 road win against the Yankees.

The Tampa Bay Rays have a .211 batting average this postseason, .316 OBP and .295 Slugging percentage. Tampa Bay’s pitching staff has a 1.67 ERA and 0.70 WHIP. Jonathan Aranda is the team’s best hitter with a .333 batting average, adding a team-high 2 RBI and 1 home run.

Drew Rasmussen (R) is the projected starting pitcher for the Rays, and he has a 1-0 record, 0.00 ERA and 0.38 WHIP in the postseason.

Cleveland Guardians Preview


The Cleveland Guardians finished the regular season with an 85-77 record and were placed 1st in the AL Central. They have a 44-37 road record and are coming off a 2-0 home win against the White Sox.

The Cleveland Guardians have a .213 batting average this postseason, .330 OBP and .350 Slugging percentage. Cleveland’s pitching staff has a 3.00 ERA and 1.11 WHIP. Patrick Bailey is the team’s best hitter with a .333 batting average. Jose Ramirez leads the team in RBI with 7, adding a team-high 2 home runs.

Foster Griffin (L) is the projected starting pitcher for the Guardians, and he has a 1-0 record, 3.38 ERA and 0.75 WHIP in the postseason.

Cleveland Guardians @ Tampa Bay Rays Betting Trends: October 12, 2026


Why the Tampa Bay Rays will win

Why the Cleveland Guardians will win

Total Runs Facts

Tampa Bay Rays Player Prop Facts

Cleveland Guardians Player Prop Facts

Matchup/League Facts

Guardians vs Rays Prediction


The Rays are 5-1 in their last 6 meetings against the Guardians and have won their last three meetings in Tampa.

In this Guardians vs Rays Prediction, the Rays are coming as -165 home favorites. I like the Rays at home in the opener of the ALCS, as they are coming off a series sweep against the Yankees and had three extra days of rest, while the Guardians are coming off a total comeback against the White Sox while they were down 0-2 and this is a big letdown spot. The Rays have swept the Guardians in their only regular season series at home with a combined 15-3 score, they have a better bullpen ERA in the playoffs and Drew Rasmussen has been red-hot, having given up one run or less in each of his last five starts. Take the Rays to win.

Nikos Lagouretos's Pick: Tampa Bay Rays ML

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