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Cincinnati Reds vs San Francisco Giants Prediction 4/8/25 MLB Picks

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San Francisco Giants (8-2) vs Cincinnati Reds (4-7)

Game Info: Tuesday, April 8, 2025 at 9:45 pm (Oracle Park)

The Line: Betting Odds: San Francisco Giants -130 / Cincinnati Reds +110 — Over/Under: 7.5

(Get latest betting odds)

In this article, we will formulate a Reds vs Giants prediction for this MLB game on Tuesday, April 8, at Oracle Park in San Francisco, California. Let’s take a look at the prediction for this MLB matchup.

Cincinnati Reds Betting Preview

The Cincinnati Reds (4-7, 2-3 Away) lost all three series early in the season. Although they secured a win in each of the series, the Reds fell to the Giants, Rangers, and Brewers. Cincinnati surprised the Giants 2-0 in the opening game of the current series, thanks to Blake Dunn, who hit a 2-RBI double in the 8th inning. Hunter Greene got a win after allowing no runs on four hits with seven strikeouts and one walk in 8.2 innings.

This year, the Reds average 3.73 runs per game (19th in the MLB) on a .207/.269/.340 triple-slash. When it comes to pitching, the Reds’ staff has a 3.09 ERA (6th) and 0.97 WHIP (2nd). Elly De La Cruz leads the Reds with a .256 batting average, two home runs, and ten RBI this season.

Nick Lodolo will take the mound for the Reds on Tuesday. The 27-year-old southpaw has a 1-1 record in two starts this year with a 1.42 ERA and 0.71 WHIP over 12.2 innings of work.

San Francisco Giants Betting Preview

The San Francisco Giants (8-2, 3-1 Home) were in a fantastic streak of seven wins before the Reds came to Oracle Park and shut them down in a 2-0 win. It was the first time this season that San Francisco failed to score a run. So far, the Giants swept the Mariners and Astros and won two of three games against the Reds in the opening series of the season. In a recent 2-0 loss, Logan Webb was great through 7.0 innings, allowing no runs on four hits with ten strikeouts and no walks.

This season, the Giants average 4.90 runs per game (10th in the MLB) on a .228/.296/.398 slash line. Regarding pitching, the Giants’ staff has a 2.77 ERA (3rd) and 1.20 WHIP (10th). Wilmer Flores leads the Giants with a .250 batting average, four home runs, and 12 RBI this season.

The projected starting pitcher for the Giants is Landen Roupp, who has a 0-0 record in one start this year with a 6.75 ERA and 2.00 WHIP in 4.0 innings.

Why the Reds will beat the Giants

Total Runs Facts

Matchup/League Facts

Reds vs Giants Prediction

The Giants won six of the previous ten H2H encounters, including three of the last five. The teams have already met four times this year, and the series is tied at 2-2. I trust Lodolo more than Roupp as he posted 2-of-2 quality starts and allowed just two earned runs in two starts, while Roupp struggled in his first start this season. I don’t think he will improve on Tuesday, which is why I am backing the Reds to prevail.

 

Oliver Zivic's Pick: Reds ML

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